Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 4.0 --

Regulon of NrdR in Lactobacillus casei ATCC 334

Properties
Regulator type: Transcription factor
TF locus tag: LSEI_1706
Regulator family: NrdR
Regulation mode: repressor
Biological process: Deoxyribonucleotide biosynthesis
Effector: Deoxyribonucleotides
Regulog: NrdR - Lactobacillaceae
Statistics of regulated genes:
- Genes 11
- Operons 5
Visualization:
Allows to visualize regulon content in the context of metabolic pathways
Built upon 81 sites [see more]
Member of regulog collections
Regulated operons
Locus Tag Name Function

Position: -133
Score: 5
Sequence: ACACACTATATAGTGT
Position: -131
Score: 5.5
Sequence: ACACTATATAGTGTAT
Locus tag: LSEI_0131
Name: nrdD
Funciton: Ribonucleotide reductase of class III (anaerobic), large subunit (EC 1.17.4.2)
nrdD
Ribonucleotide reductase of class III (anaerobic), large subunit (EC 1.17.4.2)

Position: -113
Score: 4.3
Sequence: ATACTACATCTTGGGG
Locus tag: LSEI_1742
Name: nrdG
Funciton: Ribonucleotide reductase of class III (anaerobic), activating protein (EC 1.97.1.4)
nrdG
Ribonucleotide reductase of class III (anaerobic), activating protein (EC 1.97.1.4)

Position: -31
Score: 5.3
Sequence: ATACCATATCTTGTAT
Locus tag: LSEI_2287
Name: nrdJ
Funciton: Ribonucleotide reductase of class II (coenzyme B12-dependent) (EC 1.17.4.1)
Locus tag: LSEI_2286
Name: cbrX
Funciton: Additional lipoprotein component of predicted cobalamin ECF transporter
Locus tag: LSEI_2285
Name: cbrT
Funciton: Substrate-specific component CbrT of predicted cobalamin ECF transporter
Locus tag: LSEI_2284
Name: pduO
Funciton: Cob(I)alamin adenosyltransferase PduO (EC 2.5.1.17)
nrdJ
Ribonucleotide reductase of class II (coenzyme B12-dependent) (EC 1.17.4.1)
cbrX
Additional lipoprotein component of predicted cobalamin ECF transporter
cbrT
Substrate-specific component CbrT of predicted cobalamin ECF transporter
pduO
Cob(I)alamin adenosyltransferase PduO (EC 2.5.1.17)

Position: -85
Score: 4.6
Sequence: CCCCAAGATATGGTAT
Locus tag: LSEI_1467
Name: nrdH
Funciton: Glutaredoxin-like protein NrdH
Locus tag: LSEI_1468
Name: nrdE
Funciton: Ribonucleotide reductase of class Ib (aerobic), alpha subunit (EC 1.17.4.1)
Locus tag: LSEI_1469
Name: nrdF
Funciton: Ribonucleotide reductase of class Ib (aerobic), beta subunit (EC 1.17.4.1)
nrdH
Glutaredoxin-like protein NrdH
nrdE
Ribonucleotide reductase of class Ib (aerobic), alpha subunit (EC 1.17.4.1)
nrdF
Ribonucleotide reductase of class Ib (aerobic), beta subunit (EC 1.17.4.1)

Position: -107
Score: 4.9
Sequence: CACCAATATATTGTAT
Position: -105
Score: 3.6
Sequence: CCAATATATTGTATAT
Locus tag: LSEI_1204
Name: pnuN
Funciton: NrdR-regulated deoxyribonucleotide transporter, PnuC-like
Locus tag: LSEI_1205
Name: dgk2
Funciton: Deoxyadenosine kinase (EC 2.7.1.76) / Deoxyguanosine kinase (EC 2.7.1.113)
pnuN
NrdR-regulated deoxyribonucleotide transporter, PnuC-like
dgk2
Deoxyadenosine kinase (EC 2.7.1.76) / Deoxyguanosine kinase (EC 2.7.1.113)
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