Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 4.0 --

Regulon of PurR in Lactobacillus reuteri JCM 1112

Properties
Regulator type: Transcription factor
TF locus tag: LAR_0210
Regulator family: PurR
Regulation mode: repressor
Biological process: Purine metabolism
Effector: 5-phosphoribosyl 1-pyrophosphate
Regulog: PurR - Lactobacillaceae
Statistics of regulated genes:
- Genes 15
- Operons 3
Visualization:
Allows to visualize regulon content in the context of metabolic pathways
Built upon 76 sites [see more]
Member of regulog collections
Regulated operons
Locus Tag Name Function

Position: -153
Score: 5.6
Sequence: AAACACGAACAAT
Locus tag: LAR_0131
Name: purC
Funciton: Phosphoribosylaminoimidazole-succinocarboxamide synthase (EC 6.3.2.6)
Locus tag: LAR_0132
Name: purS
Funciton: Phosphoribosylformylglycinamidine synthase, PurS subunit (EC 6.3.5.3)
Locus tag: LAR_0133
Name: purQ
Funciton: Phosphoribosylformylglycinamidine synthase, glutamine amidotransferase subunit (EC 6.3.5.3)
Locus tag: LAR_0134
Name: purL
Funciton: Phosphoribosylformylglycinamidine synthase, synthetase subunit (EC 6.3.5.3)
Locus tag: LAR_0135
Name: purF
Funciton: Amidophosphoribosyltransferase (EC 2.4.2.14)
Locus tag: LAR_0136
Name: purM
Funciton: Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1)
Locus tag: LAR_0137
Name: purN
Funciton: Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2)
Locus tag: LAR_0138
Name: purH
Funciton: IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3)
Locus tag: LAR_0139
Name: purD
Funciton: Phosphoribosylamine--glycine ligase (EC 6.3.4.13)
purC
Phosphoribosylaminoimidazole-succinocarboxamide synthase (EC 6.3.2.6)
purS
Phosphoribosylformylglycinamidine synthase, PurS subunit (EC 6.3.5.3)
purQ
Phosphoribosylformylglycinamidine synthase, glutamine amidotransferase subunit (EC 6.3.5.3)
purL
Phosphoribosylformylglycinamidine synthase, synthetase subunit (EC 6.3.5.3)
purF
Amidophosphoribosyltransferase (EC 2.4.2.14)
purM
Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1)
purN
Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2)
purH
IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3)
purD
Phosphoribosylamine--glycine ligase (EC 6.3.4.13)

Position: -102
Score: 4.9
Sequence: ATACACGAACTAT
Locus tag: LAR_0128
Name: purE
Funciton: Phosphoribosylaminoimidazole carboxylase catalytic subunit (EC 4.1.1.21)
Locus tag: LAR_0129
Name: purK
Funciton: Phosphoribosylaminoimidazole carboxylase ATPase subunit (EC 4.1.1.21)
Locus tag: LAR_0130
Name: purB
Funciton: Adenylosuccinate lyase (EC 4.3.2.2)
purE
Phosphoribosylaminoimidazole carboxylase catalytic subunit (EC 4.1.1.21)
purK
Phosphoribosylaminoimidazole carboxylase ATPase subunit (EC 4.1.1.21)
purB
Adenylosuccinate lyase (EC 4.3.2.2)

Position: -64
Score: 5.2
Sequence: AAATCCGAACATT
Locus tag: LAR_0210
Name: purR
Funciton: Purine metabolism transcriptional regulator PurR, PurR family
Locus tag: LAR_0211
Name: glmU
Funciton: N-acetylglucosamine-1-phosphate uridyltransferase (EC 2.7.7.23) / Glucosamine-1-phosphate N-acetyltransferase (EC 2.3.1.157)
Locus tag: LAR_0212
Name: prsA
Funciton: Ribose-phosphate pyrophosphokinase (EC 2.7.6.1)
purR
Purine metabolism transcriptional regulator PurR, PurR family
glmU
N-acetylglucosamine-1-phosphate uridyltransferase (EC 2.7.7.23) / Glucosamine-1-phosphate N-acetyltransferase (EC 2.3.1.157)
prsA
Ribose-phosphate pyrophosphokinase (EC 2.7.6.1)
Export
Regulated Genes [ Tab delimited format ] DOWNLOAD
Regulatory Sites [ FASTA format ] DOWNLOAD