Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 4.0 --

Regulon of PurR in Lactobacillus plantarum WCFS1

Properties
Regulator type: Transcription factor
TF locus tag: lp_0466
Regulator family: PurR
Regulation mode: repressor
Biological process: Purine metabolism
Effector: 5-phosphoribosyl 1-pyrophosphate
Regulog: PurR - Lactobacillaceae
Statistics of regulated genes:
- Genes 17
- Operons 5
Visualization:
Allows to visualize regulon content in the context of metabolic pathways
Built upon 76 sites [see more]
Member of regulog collections
Regulated operons
Locus Tag Name Function

Position: -104
Score: 5
Sequence: TAACACGAACATT
Locus tag: lp_2729
Name: purE
Funciton: Phosphoribosylaminoimidazole carboxylase catalytic subunit (EC 4.1.1.21)
Locus tag: lp_2728
Name: purK
Funciton: Phosphoribosylaminoimidazole carboxylase ATPase subunit (EC 4.1.1.21)
Locus tag: lp_2727
Name: purC
Funciton: Phosphoribosylaminoimidazole-succinocarboxamide synthase (EC 6.3.2.6)
Locus tag: lp_2726
Name: purS
Funciton: Phosphoribosylformylglycinamidine synthase, PurS subunit (EC 6.3.5.3)
Locus tag: lp_2725
Name: purQ
Funciton: Phosphoribosylformylglycinamidine synthase, glutamine amidotransferase subunit (EC 6.3.5.3)
Locus tag: lp_2724
Name: purL
Funciton: Phosphoribosylformylglycinamidine synthase, synthetase subunit (EC 6.3.5.3)
Locus tag: lp_2723
Name: purF
Funciton: Amidophosphoribosyltransferase (EC 2.4.2.14)
Locus tag: lp_2722
Name: purM
Funciton: Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1)
Locus tag: lp_2721
Name: purN
Funciton: Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2)
Locus tag: lp_2720
Name: purH
Funciton: IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3)
Locus tag: lp_2719
Name: purD
Funciton: Phosphoribosylamine--glycine ligase (EC 6.3.4.13)
purE
Phosphoribosylaminoimidazole carboxylase catalytic subunit (EC 4.1.1.21)
purK
Phosphoribosylaminoimidazole carboxylase ATPase subunit (EC 4.1.1.21)
purC
Phosphoribosylaminoimidazole-succinocarboxamide synthase (EC 6.3.2.6)
purS
Phosphoribosylformylglycinamidine synthase, PurS subunit (EC 6.3.5.3)
purQ
Phosphoribosylformylglycinamidine synthase, glutamine amidotransferase subunit (EC 6.3.5.3)
purL
Phosphoribosylformylglycinamidine synthase, synthetase subunit (EC 6.3.5.3)
purF
Amidophosphoribosyltransferase (EC 2.4.2.14)
purM
Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1)
purN
Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2)
purH
IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3)
purD
Phosphoribosylamine--glycine ligase (EC 6.3.4.13)

Position: -201
Score: 4.3
Sequence: AAAACCGAATGTT
Locus tag: lp_3269
Name: purB
Funciton: Adenylosuccinate lyase (EC 4.3.2.2)
purB
Adenylosuccinate lyase (EC 4.3.2.2)

Position: -280
Score: 5.6
Sequence: AAACACGAACATT
Position: -239
Score: 4.5
Sequence: AGAGACGAACAAT
Position: -135
Score: 5.1
Sequence: AAACAAGAACATT
Locus tag: lp_3270
Name: purA
Funciton: Adenylosuccinate synthetase (EC 6.3.4.4)
Locus tag: lp_3271
Name: guaC
Funciton: GMP reductase (EC 1.7.1.7)
purA
Adenylosuccinate synthetase (EC 6.3.4.4)
guaC
GMP reductase (EC 1.7.1.7)

Position: -57
Score: 5.3
Sequence: AAACACGAACGTT
Locus tag: lp_0848
Name: pbuG
Funciton: Guanine/hypoxanthine permease
pbuG
Guanine/hypoxanthine permease

Position: 12
Score: 4.3
Sequence: AGAAGCGAACGTT
Locus tag: lp_0466
Name: purR
Funciton: Purine metabolism transcriptional regulator PurR, PurR family
Locus tag: lp_0467
Name: glmU
Funciton: N-acetylglucosamine-1-phosphate uridyltransferase (EC 2.7.7.23) / Glucosamine-1-phosphate N-acetyltransferase (EC 2.3.1.157)
purR
Purine metabolism transcriptional regulator PurR, PurR family
glmU
N-acetylglucosamine-1-phosphate uridyltransferase (EC 2.7.7.23) / Glucosamine-1-phosphate N-acetyltransferase (EC 2.3.1.157)
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Regulated Genes [ Tab delimited format ] DOWNLOAD
Regulatory Sites [ FASTA format ] DOWNLOAD