Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 4.0 --

Regulon of PurR in Lactobacillus fermentum IFO 3956

Properties
Regulator type: Transcription factor
TF locus tag: LAF_0194
Regulator family: PurR
Regulation mode: repressor
Biological process: Purine metabolism
Effector: 5-phosphoribosyl 1-pyrophosphate
Regulog: PurR - Lactobacillaceae
Statistics of regulated genes:
- Genes 16
- Operons 5
Visualization:
Allows to visualize regulon content in the context of metabolic pathways
Built upon 76 sites [see more]
Member of regulog collections
Regulated operons
Locus Tag Name Function

Position: -155
Score: 5.6
Sequence: AAACACGAACATT
Locus tag: LAF_0124
Name: purC
Funciton: Phosphoribosylaminoimidazole-succinocarboxamide synthase (EC 6.3.2.6)
Locus tag: LAF_0125
Name: purS
Funciton: Phosphoribosylformylglycinamidine synthase, PurS subunit (EC 6.3.5.3)
Locus tag: LAF_0126
Name: purQ
Funciton: Phosphoribosylformylglycinamidine synthase, glutamine amidotransferase subunit (EC 6.3.5.3)
Locus tag: LAF_0127
Name: purL
Funciton: Phosphoribosylformylglycinamidine synthase, synthetase subunit (EC 6.3.5.3)
Locus tag: LAF_0128
Name: purF
Funciton: Amidophosphoribosyltransferase (EC 2.4.2.14)
Locus tag: LAF_0129
Name: purM
Funciton: Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1)
Locus tag: LAF_0130
Name: purN
Funciton: Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2)
Locus tag: LAF_0131
Name: purH
Funciton: IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3)
purC
Phosphoribosylaminoimidazole-succinocarboxamide synthase (EC 6.3.2.6)
purS
Phosphoribosylformylglycinamidine synthase, PurS subunit (EC 6.3.5.3)
purQ
Phosphoribosylformylglycinamidine synthase, glutamine amidotransferase subunit (EC 6.3.5.3)
purL
Phosphoribosylformylglycinamidine synthase, synthetase subunit (EC 6.3.5.3)
purF
Amidophosphoribosyltransferase (EC 2.4.2.14)
purM
Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1)
purN
Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2)
purH
IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3)

Position: -123
Score: 5.3
Sequence: AAAACCGAACAAT
Locus tag: LAF_0044
Name: purA
Funciton: Adenylosuccinate synthetase (EC 6.3.4.4)
purA
Adenylosuccinate synthetase (EC 6.3.4.4)

Position: -106
Score: 5.2
Sequence: AAATCCGAACAAT
Locus tag: LAF_0118
Name: purE
Funciton: Phosphoribosylaminoimidazole carboxylase catalytic subunit (EC 4.1.1.21)
Locus tag: LAF_0119
Name: purK
Funciton: Phosphoribosylaminoimidazole carboxylase ATPase subunit (EC 4.1.1.21)
Locus tag: LAF_0120
Name: purB
Funciton: Adenylosuccinate lyase (EC 4.3.2.2)
purE
Phosphoribosylaminoimidazole carboxylase catalytic subunit (EC 4.1.1.21)
purK
Phosphoribosylaminoimidazole carboxylase ATPase subunit (EC 4.1.1.21)
purB
Adenylosuccinate lyase (EC 4.3.2.2)

Position: -67
Score: 4.3
Sequence: AAAGCCGAATATT
Locus tag: LAF_1806
Name: pbuG
Funciton: Guanine/hypoxanthine permease
pbuG
Guanine/hypoxanthine permease

Position: -98
Score: 5.2
Sequence: AAAGACGAACAAT
Locus tag: LAF_0194
Name: purR
Funciton: Purine metabolism transcriptional regulator PurR, PurR family
Locus tag: LAF_0195
Name: glmU
Funciton: N-acetylglucosamine-1-phosphate uridyltransferase (EC 2.7.7.23) / Glucosamine-1-phosphate N-acetyltransferase (EC 2.3.1.157)
Locus tag: LAF_0196
Name: prsA
Funciton: Ribose-phosphate pyrophosphokinase (EC 2.7.6.1)
purR
Purine metabolism transcriptional regulator PurR, PurR family
glmU
N-acetylglucosamine-1-phosphate uridyltransferase (EC 2.7.7.23) / Glucosamine-1-phosphate N-acetyltransferase (EC 2.3.1.157)
prsA
Ribose-phosphate pyrophosphokinase (EC 2.7.6.1)
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