Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 4.0 --

Regulon of PurR in Lactobacillus casei ATCC 334

Properties
Regulator type: Transcription factor
TF locus tag: LSEI_2587
Regulator family: PurR
Regulation mode: repressor
Biological process: Purine metabolism
Effector: 5-phosphoribosyl 1-pyrophosphate
Regulog: PurR - Lactobacillaceae
Statistics of regulated genes:
- Genes 15
- Operons 5
Visualization:
Allows to visualize regulon content in the context of metabolic pathways
Built upon 76 sites [see more]
Member of regulog collections
Regulated operons
Locus Tag Name Function

Position: -135
Score: 5.6
Sequence: AAACACGAACATT
Locus tag: LSEI_0911
Name: guaC
Funciton: GMP reductase (EC 1.7.1.7)
guaC
GMP reductase (EC 1.7.1.7)

Position: -107
Score: 5.3
Sequence: AAACACGAACGAT
Locus tag: LSEI_1756
Name: purE
Funciton: Phosphoribosylaminoimidazole carboxylase catalytic subunit (EC 4.1.1.21)
Locus tag: LSEI_1755
Name: purK
Funciton: Phosphoribosylaminoimidazole carboxylase ATPase subunit (EC 4.1.1.21)
Locus tag: LSEI_1754
Name: purC
Funciton: Phosphoribosylaminoimidazole-succinocarboxamide synthase (EC 6.3.2.6)
Locus tag: LSEI_1753
Name: purS
Funciton: Phosphoribosylformylglycinamidine synthase, PurS subunit (EC 6.3.5.3)
Locus tag: LSEI_1752
Name: purQ
Funciton: Phosphoribosylformylglycinamidine synthase, glutamine amidotransferase subunit (EC 6.3.5.3)
Locus tag: LSEI_1751
Name: purL
Funciton: Phosphoribosylformylglycinamidine synthase, synthetase subunit (EC 6.3.5.3)
Locus tag: LSEI_1750
Name: purF
Funciton: Amidophosphoribosyltransferase (EC 2.4.2.14)
Locus tag: LSEI_1749
Name: purM
Funciton: Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1)
Locus tag: LSEI_1748
Name: purN
Funciton: Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2)
Locus tag: LSEI_1747
Name: purH
Funciton: IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3)
Locus tag: LSEI_1746
Name: purD
Funciton: Phosphoribosylamine--glycine ligase (EC 6.3.4.13)
purE
Phosphoribosylaminoimidazole carboxylase catalytic subunit (EC 4.1.1.21)
purK
Phosphoribosylaminoimidazole carboxylase ATPase subunit (EC 4.1.1.21)
purC
Phosphoribosylaminoimidazole-succinocarboxamide synthase (EC 6.3.2.6)
purS
Phosphoribosylformylglycinamidine synthase, PurS subunit (EC 6.3.5.3)
purQ
Phosphoribosylformylglycinamidine synthase, glutamine amidotransferase subunit (EC 6.3.5.3)
purL
Phosphoribosylformylglycinamidine synthase, synthetase subunit (EC 6.3.5.3)
purF
Amidophosphoribosyltransferase (EC 2.4.2.14)
purM
Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1)
purN
Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2)
purH
IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3)
purD
Phosphoribosylamine--glycine ligase (EC 6.3.4.13)

Position: -107
Score: 5.6
Sequence: AAACACGAACATT
Locus tag: LSEI_0151
Name: pbuO
Funciton: Guanine/hypoxanthine permease
pbuO
Guanine/hypoxanthine permease

Position: -235
Score: 4.5
Sequence: AAAAACGAATGAT
Position: -194
Score: 5.3
Sequence: AAAACCGAACATT
Locus tag: LSEI_0217
Name: guaB
Funciton: Inosine-5'-monophosphate dehydrogenase (EC 1.1.1.205)
guaB
Inosine-5'-monophosphate dehydrogenase (EC 1.1.1.205)

Position: -126
Score: 4.8
Sequence: AAATGCGAACGTT
Locus tag: LSEI_2587
Name: purR
Funciton: Purine metabolism transcriptional regulator PurR, PurR family
purR
Purine metabolism transcriptional regulator PurR, PurR family
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