Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 4.0 --

Regulon of CcpA in Pediococcus pentosaceus ATCC 25745

Properties
Regulator type: Transcription factor
TF locus tag: PEPE_1250
Regulator family: LacI
Regulation mode:
Biological process: Carbon catabolism
Effector: HPr, phosphocarrier protein; Fructose-1,6-bisphosphate
Regulog: CcpA - Lactobacillaceae
Statistics of regulated genes:
- Genes 83
- Operons 42
Visualization:
Allows to visualize regulon content in the context of metabolic pathways
Built upon 561 sites [see more]
Member of regulog collections
Regulated operons
Locus Tag Name Function

Position: -150
Score: 4.2
Sequence: TTGTAAGCGAATACAC
Position: -129
Score: 4.4
Sequence: ATGTCAACGCTTTTAT
Position: -107
Score: 4.7
Sequence: TTGAAAACGCTTTACA
Locus tag: PEPE_0185
Name: xynT
Funciton: Na+/xyloside symporter
Locus tag: PEPE_0186
Name: xylR
Funciton: Xylose repressor XylR, ROK family
Locus tag: PEPE_0187
Name: xylA
Funciton: Xylose isomerase (EC 5.3.1.5)
Locus tag: PEPE_0188
Name: xylB
Funciton: Xylulose kinase (EC 2.7.1.17)
xynT
Na+/xyloside symporter
xylR
Xylose repressor XylR, ROK family
xylA
Xylose isomerase (EC 5.3.1.5)
xylB
Xylulose kinase (EC 2.7.1.17)

Position: -103
Score: 4.3
Sequence: TTGATAGCCTTTTCAT
Locus tag: PEPE_0412
Name: guaA
Funciton: GMP synthase (EC 6.3.5.2)
guaA
GMP synthase (EC 6.3.5.2)

Position: -65
Score: 4.9
Sequence: ATTAAAACGTTTTCAT
Locus tag: PEPE_1699
Name: rbsK
Funciton: Ribokinase (EC 2.7.1.15)
Locus tag: PEPE_1698
Name: rbsD
Funciton: Ribose ABC transport system, high affinity permease RbsD (TC 3.A.1.2.1)
Locus tag: PEPE_1697
Name: rbsU
Funciton: Ribose uptake protein RbsU (TC 2.A.7.5)
rbsK
Ribokinase (EC 2.7.1.15)
rbsD
Ribose ABC transport system, high affinity permease RbsD (TC 3.A.1.2.1)
rbsU
Ribose uptake protein RbsU (TC 2.A.7.5)

Position: -140
Score: 4.2
Sequence: ATATAAGCGTTTAATT
Locus tag: PEPE_1700
Name: rbsR
Funciton: Ribose operon transcriptional regulator, LacI family
rbsR
Ribose operon transcriptional regulator, LacI family

Position: -84
Score: 4.2
Sequence: TTAAAAACGATTTATA
Position: -51
Score: 5
Sequence: TAGAAAGCGCTTTCTT
Locus tag: PEPE_1623
Name: glpK
Funciton: Glycerol kinase (EC 2.7.1.30)
Locus tag: PEPE_1624
Name: glpD
Funciton: Alpha-glycerophosphate oxidase (EC 1.1.3.21)
Locus tag: PEPE_1625
Name: glpF
Funciton: Glycerol uptake facilitator protein
glpK
Glycerol kinase (EC 2.7.1.30)
glpD
Alpha-glycerophosphate oxidase (EC 1.1.3.21)
glpF
Glycerol uptake facilitator protein

Position: -38
Score: 4.6
Sequence: ACGAAAACGTTTTCAA
Locus tag: PEPE_1252
Name: spxB
Funciton: Pyruvate oxidase (EC 1.2.3.3)
spxB
Pyruvate oxidase (EC 1.2.3.3)

Position: -75
Score: 4.9
Sequence: TTGTAAGCGGTTTTAT
Locus tag: PEPE_0144
Name: fbp
Funciton: Fructose-1,6-bisphosphatase, Bacillus type (EC 3.1.3.11)
fbp
Fructose-1,6-bisphosphatase, Bacillus type (EC 3.1.3.11)

Position: -88
Score: 4.8
Sequence: GTGAAAGCGCTAACAT
Locus tag: PEPE_0697
Name: lrgA
Funciton: Antiholin-like protein LrgA
Locus tag: PEPE_0698
Name: lrgB
Funciton: LrgA-associated membrane protein LrgB
lrgA
Antiholin-like protein LrgA
lrgB
LrgA-associated membrane protein LrgB

Position: -21
Score: 4.3
Sequence: ATGAAAGGGGTTTTAT
Locus tag: PEPE_1334
Name: pmi
Funciton: Mannose-6-phosphate isomerase (EC 5.3.1.8)
pmi
Mannose-6-phosphate isomerase (EC 5.3.1.8)

Position: -199
Score: 4.6
Sequence: TTAGAAACGCTTACAT
Position: -56
Score: 4.7
Sequence: TAGCAAGCGCTTACAA
Locus tag: PEPE_1804
Name: treP
Funciton: Trehalose-specific PTS system, EIIABC component (EC 2.7.1.69)
treP
Trehalose-specific PTS system, EIIABC component (EC 2.7.1.69)

Position: -177
Score: 4.7
Sequence: TTGTAAGCGCTTGCTA
Position: -34
Score: 4.6
Sequence: ATGTAAGCGTTTCTAA
Locus tag: PEPE_1805
Name: treR
Funciton: Trehalose utilization transcriptional regulator TreR, GntR family
Locus tag: PEPE_1806
Name: treA
Funciton: Trehalose-6-phosphate hydrolase (EC 3.2.1.93)
treR
Trehalose utilization transcriptional regulator TreR, GntR family
treA
Trehalose-6-phosphate hydrolase (EC 3.2.1.93)

Position: -146
Score: 4.5
Sequence: TTGAAAGCGTTTTTTG
Locus tag: PEPE_1518
Name: manL
Funciton: Mannose-specific PTS system, IIAB component (EC 2.7.1.69)
Locus tag: PEPE_1517
Name: manM
Funciton: Mannose-specific PTS system, IIC component (EC 2.7.1.69)
Locus tag: PEPE_1516
Name: manN
Funciton: Mannose-specific PTS system, IID component (EC 2.7.1.69)
Locus tag: PEPE_1515
Name: manO
Funciton: Predicted regulator of the mannose operon, ManO
manL
Mannose-specific PTS system, IIAB component (EC 2.7.1.69)
manM
Mannose-specific PTS system, IIC component (EC 2.7.1.69)
manN
Mannose-specific PTS system, IID component (EC 2.7.1.69)
manO
Predicted regulator of the mannose operon, ManO

Position: -231
Score: 4.3
Sequence: TAGCAAGCGCTTTCAC
Position: -167
Score: 4.9
Sequence: TTTAAAACGTTTTCAT
Locus tag: PEPE_1632
Name: ycbB
Funciton: Signal transduction response regulator
ycbB
Signal transduction response regulator

Position: -51
Score: 4.5
Sequence: ATGAAAAGGCTTTCTA
Locus tag: PEPE_0106
Name: bglA
Funciton: 6-phospho-beta-glucosidase (EC 3.2.1.86)
bglA
6-phospho-beta-glucosidase (EC 3.2.1.86)

Position: -204
Score: 4.7
Sequence: TTGTATCCGTTTTCAT
Locus tag: PEPE_0511
Name: rafR
Funciton: Raffinose utilization transcriptional regulator RafR, AraC family
rafR
Raffinose utilization transcriptional regulator RafR, AraC family

Position: -39
Score: 4.4
Sequence: ATGAAAGCGCTTCATA
Locus tag: PEPE_0968
Name: malT
Funciton: Predicted maltose/maltodextrin permease
Locus tag: PEPE_0967
Name: mapA
Funciton: Maltose phosphorylase (EC 2.4.1.8) / Trehalose phosphorylase (EC 2.4.1.64)
Locus tag: PEPE_0966
Name: pgmB
Funciton: Beta-phosphoglucomutase (EC 5.4.2.6)
malT
Predicted maltose/maltodextrin permease
mapA
Maltose phosphorylase (EC 2.4.1.8) / Trehalose phosphorylase (EC 2.4.1.64)
pgmB
Beta-phosphoglucomutase (EC 5.4.2.6)

Position: -141
Score: 4.7
Sequence: TTGAATTCGCTTTCAT
Locus tag: PEPE_1777
Name: lhv_0924
Funciton: Predicted transcriptional regulator, GntR family
lhv_0924
Predicted transcriptional regulator, GntR family

Position: -116
Score: 4
Sequence: AATAAAGCACTTACAT
Locus tag: PEPE_1093
Name: pfk
Funciton: 6-phosphofructokinase (EC 2.7.1.11)
Locus tag: PEPE_1092
Name: pyk
Funciton: Pyruvate kinase (EC 2.7.1.40)
pfk
6-phosphofructokinase (EC 2.7.1.11)
pyk
Pyruvate kinase (EC 2.7.1.40)

Position: -104
Score: 4.1
Sequence: ATAAAAACGTTTAACT
Position: -71
Score: 4.7
Sequence: TTGTAAACGGATACAT
Position: -15
Score: 4
Sequence: AAGAAGGCGTTTAAAA
Locus tag: PEPE_0276
Name: dhaT
Funciton: 1,3-propanediol dehydrogenase (EC 1.1.1.202)
dhaT
1,3-propanediol dehydrogenase (EC 1.1.1.202)

Position: -75
Score: 4.8
Sequence: TTGCAAACGCTTTCTT
Locus tag: PEPE_0182
Name: adhX
Funciton: Zn conatining alcohol dehydrogenase
adhX
Zn conatining alcohol dehydrogenase

Position: -55
Score: 4.8
Sequence: ATGAAAGCGTATTCTT
Locus tag: PEPE_1821
Name: gabD
Funciton: Succinate-semialdehyde dehydrogenase [NAD] (EC 1.2.1.24); Succinate-semialdehyde dehydrogenase [NADP+] (EC 1.2.1.16)
gabD
Succinate-semialdehyde dehydrogenase [NAD] (EC 1.2.1.24); Succinate-semialdehyde dehydrogenase [NADP+] (EC 1.2.1.16)

Position: -109
Score: 4.6
Sequence: ATGAATACGTTATCAA
Locus tag: PEPE_1251
Name: pepQ
Funciton: Xaa-Pro dipeptidase (EC 3.4.13.9)
pepQ
Xaa-Pro dipeptidase (EC 3.4.13.9)

Position: -127
Score: 4
Sequence: ATGTAAGGGCTTGCTT
Locus tag: PEPE_0609
Name: ptsH
Funciton: Phosphotransferase system, HPr-related protein
Locus tag: PEPE_0610
Name: ptsI
Funciton: Phosphoenolpyruvate-protein kinase, PTS system component (EC 2.7.3.9)
ptsH
Phosphotransferase system, HPr-related protein
ptsI
Phosphoenolpyruvate-protein kinase, PTS system component (EC 2.7.3.9)

Position: -213
Score: 4.3
Sequence: ATGCAAGCGCTTTACA
Position: -59
Score: 4.6
Sequence: GTGTAAGCGGTTTTAT
Locus tag: PEPE_0519
Name: scrB
Funciton: Sucrose-6-phosphate hydrolase (EC 3.2.1.26)
Locus tag: PEPE_0520
Name: scrR
Funciton: Sucrose operon repressor ScrR, LacI family
Locus tag: PEPE_0521
Name: agl4
Funciton: Oligo-1,6-glucosidase (EC 3.2.1.10)
scrB
Sucrose-6-phosphate hydrolase (EC 3.2.1.26)
scrR
Sucrose operon repressor ScrR, LacI family
agl4
Oligo-1,6-glucosidase (EC 3.2.1.10)

Position: -45
Score: 4.7
Sequence: ATGAAAGCGGTATCTT
Locus tag: PEPE_0112
Name: yghZ
Funciton: Predicted oxidoreductase, aryl-alcohol dehydrogenase related
yghZ
Predicted oxidoreductase, aryl-alcohol dehydrogenase related

Position: -58
Score: 4.5
Sequence: TCGTAAGCGGTTTCAT
Locus tag: PEPE_0281
Name: pts20B
Funciton: PTS system, cellobiose-specific IIB component (EC 2.7.1.69)
Locus tag: PEPE_0282
Name: pts20A
Funciton: PTS system, cellobiose-specific IIA component (EC 2.7.1.69)
Locus tag: PEPE_0283
Name: bglA
Funciton: 6-phospho-beta-glucosidase (EC 3.2.1.86)
pts20B
PTS system, cellobiose-specific IIB component (EC 2.7.1.69)
pts20A
PTS system, cellobiose-specific IIA component (EC 2.7.1.69)
bglA
6-phospho-beta-glucosidase (EC 3.2.1.86)

Position: -35
Score: 4.7
Sequence: AAGAAAGCGGTTACTT
Locus tag: PEPE_1360
Name: gntP
Funciton: H+/gluconate symporter related permease
gntP
H+/gluconate symporter related permease

Position: -212
Score: 4.3
Sequence: ATAAAACCGCTTACAC
Position: -157
Score: 4
Sequence: ATGTCAGCGTTTCAAA
Position: -58
Score: 4.1
Sequence: TGTAAAGCGCTTGCAT
Locus tag: PEPE_0518
Name: scrA
Funciton: Sucrose-specific PTS system, IIABC component (EC 2.7.1.69)
scrA
Sucrose-specific PTS system, IIABC component (EC 2.7.1.69)

Position: -107
Score: 4
Sequence: TTTAAAACATTTTAAA
Position: -40
Score: 4.8
Sequence: TAGAAAGCGCTTCCAT
Locus tag: PEPE_1774
Name: lplA1
Funciton: Lipoate-protein ligase A
Locus tag: PEPE_1773
Name: pdhA
Funciton: Dihydrolipoamide dehydrogenase complex (EC 1.8.1.4), E1 component alpha-subunit
Locus tag: PEPE_1772
Name: pdhB
Funciton: Dihydrolipoamide dehydrogenase complex (EC 1.8.1.4), E1 component beta-subunit
Locus tag: PEPE_1771
Name: pdhC
Funciton: Dihydrolipoamide dehydrogenase complex (EC 1.8.1.4), E2 component
Locus tag: PEPE_1770
Name: pdhD
Funciton: Dihydrolipoamide dehydrogenase complex (EC 1.8.1.4), E3 component
lplA1
Lipoate-protein ligase A
pdhA
Dihydrolipoamide dehydrogenase complex (EC 1.8.1.4), E1 component alpha-subunit
pdhB
Dihydrolipoamide dehydrogenase complex (EC 1.8.1.4), E1 component beta-subunit
pdhC
Dihydrolipoamide dehydrogenase complex (EC 1.8.1.4), E2 component
pdhD
Dihydrolipoamide dehydrogenase complex (EC 1.8.1.4), E3 component

Position: -41
Score: 4.8
Sequence: TTGTAAGCGTTTTATA
Locus tag: PEPE_0205
Name: lacL
Funciton: Beta-galactosidase large subunit (EC 3.2.1.23)
Locus tag: PEPE_0204
Name: lacM
Funciton: Beta-galactosidase small subunit (EC 3.2.1.23)
lacL
Beta-galactosidase large subunit (EC 3.2.1.23)
lacM
Beta-galactosidase small subunit (EC 3.2.1.23)

Position: -181
Score: 5.1
Sequence: TTGTAAGCGTTATCAT
Locus tag: PEPE_0479
Name: lp_0827
Funciton: Conserved hypothetical protein
lp_0827
Conserved hypothetical protein

Position: -6
Score: 4.3
Sequence: ATGAAAGTGCTTACAG
Locus tag: PEPE_1166
Name: fruR
Funciton: Fructose utilization transcriptional regulator FruR, DeoR family
Locus tag: PEPE_1165
Name: fruB
Funciton: 1-phosphofructokinase (EC 2.7.1.56)
Locus tag: PEPE_1164
Name: fruA
Funciton: Fructose-specific PTS system, IIABC component (EC 2.7.1.69)
fruR
Fructose utilization transcriptional regulator FruR, DeoR family
fruB
1-phosphofructokinase (EC 2.7.1.56)
fruA
Fructose-specific PTS system, IIABC component (EC 2.7.1.69)

Position: -69
Score: 4.6
Sequence: TTGATAACGTATTCAT
Locus tag: PEPE_1250
Name: ccpA
Funciton: Carbon catabolism global transcriptional regulator CcpA, LacI family
ccpA
Carbon catabolism global transcriptional regulator CcpA, LacI family

Position: -63
Score: 4.8
Sequence: TTGTAATCGCTTTCTA
Locus tag: PEPE_1662
Name: dhaK
Funciton: Phosphoenolpyruvate-dihydroxyacetone phosphotransferase (EC 2.7.1.121), dihydroxyacetone binding subunit DhaK
Locus tag: PEPE_1661
Name: dhaL
Funciton: Phosphoenolpyruvate-dihydroxyacetone phosphotransferase (EC 2.7.1.121), ADP-binding subunit DhaL
Locus tag: PEPE_1660
Name: dhaM
Funciton: Phosphoenolpyruvate-dihydroxyacetone phosphotransferase (EC 2.7.1.121), subunit DhaM; DHA-specific IIA component
dhaK
Phosphoenolpyruvate-dihydroxyacetone phosphotransferase (EC 2.7.1.121), dihydroxyacetone binding subunit DhaK
dhaL
Phosphoenolpyruvate-dihydroxyacetone phosphotransferase (EC 2.7.1.121), ADP-binding subunit DhaL
dhaM
Phosphoenolpyruvate-dihydroxyacetone phosphotransferase (EC 2.7.1.121), subunit DhaM; DHA-specific IIA component

Position: -46
Score: 4.7
Sequence: ATGAAAACGGATACAA
Locus tag: PEPE_0512
Name: lacS
Funciton: Lactose and galactose permease
lacS
Lactose and galactose permease

Position: -83
Score: 4.5
Sequence: TTGGAAACGCTTTATT
Locus tag: PEPE_0189
Name: ptcA
Funciton: Putrescine carbamoyltransferase (EC 2.1.3.6)
Locus tag: PEPE_0190
Name: aguD
Funciton: Agmatine:putrescine antiporter
Locus tag: PEPE_0191
Name: aguA1
Funciton: Agmatine iminohydrolase (EC 3.5.3.12)
Locus tag: PEPE_0192
Name: arcC2
Funciton: Carbamate kinase (EC 2.7.2.2)
Locus tag: PEPE_0193
Name: aguA2
Funciton: Agmatine iminohydrolase (EC 3.5.3.12)
Locus tag: PEPE_0194
Name: LVIS_2205
Funciton: Transcriptional regulator, RpiR family
ptcA
Putrescine carbamoyltransferase (EC 2.1.3.6)
aguD
Agmatine:putrescine antiporter
aguA1
Agmatine iminohydrolase (EC 3.5.3.12)
arcC2
Carbamate kinase (EC 2.7.2.2)
aguA2
Agmatine iminohydrolase (EC 3.5.3.12)
LVIS_2205
Transcriptional regulator, RpiR family

Position: -77
Score: 4.1
Sequence: AAAAAAACGCTTTCTG
Locus tag: PEPE_0446
Name: null
Funciton: Phosphoglucomutase (EC 5.4.2.2)
Phosphoglucomutase (EC 5.4.2.2)

Position: -76
Score: 4.3
Sequence: AAGAAAGCCTTTACAT
Locus tag: PEPE_1763
Name: lacX
Funciton: Aldose 1-epimerase
lacX
Aldose 1-epimerase

Position: -119
Score: 5
Sequence: ATGAAAACGTTTTAAA
Position: -55
Score: 4.5
Sequence: GTGAAAGCGCTTGCTA
Locus tag: PEPE_1631
Name: arcB
Funciton: Ornithine carbamoyltransferase (EC 2.1.3.3)
Locus tag: PEPE_1630
Name: arcC
Funciton: Carbamate kinase (EC 2.7.2.2)
Locus tag: PEPE_1629
Name: arcA
Funciton: Arginine deiminase (EC 3.5.3.6)
Locus tag: PEPE_1628
Name: arcD
Funciton: Arginine/ornithine antiporter ArcD
arcB
Ornithine carbamoyltransferase (EC 2.1.3.3)
arcC
Carbamate kinase (EC 2.7.2.2)
arcA
Arginine deiminase (EC 3.5.3.6)
arcD
Arginine/ornithine antiporter ArcD

Position: -48
Score: 4.9
Sequence: ATGAATACGCTTTCAA
Locus tag: PEPE_0162
Name: araE
Funciton: Arabinose-proton symporter
Locus tag: PEPE_0163
Name: araB
Funciton: Ribulokinase (EC 2.7.1.16)
Locus tag: PEPE_0164
Name: araD
Funciton: L-ribulose-5-phosphate 4-epimerase (EC 5.1.3.4)
Locus tag: PEPE_0165
Name: araA
Funciton: L-arabinose isomerase (EC 5.3.1.4)
araE
Arabinose-proton symporter
araB
Ribulokinase (EC 2.7.1.16)
araD
L-ribulose-5-phosphate 4-epimerase (EC 5.1.3.4)
araA
L-arabinose isomerase (EC 5.3.1.4)

Position: -34
Score: 4.8
Sequence: ATGAAAGCGAATTCAA
Locus tag: PEPE_1776
Name: bglB
Funciton: Beta-glucosidase (EC 3.2.1.21); 6-phospho-beta-glucosidase (EC 3.2.1.86)
Locus tag: PEPE_1775
Name: LBA0884
Funciton: PTS system, IIC component
bglB
Beta-glucosidase (EC 3.2.1.21); 6-phospho-beta-glucosidase (EC 3.2.1.86)
LBA0884
PTS system, IIC component

Position: -81
Score: 4.7
Sequence: TTATAAGCGTTTTAAT
Position: -66
Score: 4.1
Sequence: TTGTAAGCGGTTCACA
Locus tag: PEPE_1619
Name: hcaD
Funciton: NADH peroxidase (EC 1.11.1.1)
hcaD
NADH peroxidase (EC 1.11.1.1)
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