Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 4.0 --

Regulon of CcpA in Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293

Properties
Regulator type: Transcription factor
TF locus tag: LEUM_0544
Regulator family: LacI
Regulation mode:
Biological process: Carbon catabolism
Effector: HPr, phosphocarrier protein; Fructose-1,6-bisphosphate
Regulog: CcpA - Lactobacillaceae
Statistics of regulated genes:
- Genes 77
- Operons 32
Visualization:
Allows to visualize regulon content in the context of metabolic pathways
Built upon 561 sites [see more]
Member of regulog collections
Regulated operons
Locus Tag Name Function

Position: -52
Score: 5.1
Sequence: TAGTAAGCGCTTACAT
Locus tag: LEUM_1245
Name: xynT
Funciton: Na+/xyloside symporter
xynT
Na+/xyloside symporter

Position: -107
Score: 4.1
Sequence: TTGTATACTGTTTCAT
Locus tag: LEUM_1881
Name: coaA
Funciton: Pantothenate kinase (EC 2.7.1.33)
coaA
Pantothenate kinase (EC 2.7.1.33)

Position: -45
Score: 5.4
Sequence: ATGAAAGCGCTTACAA
Locus tag: LEUM_0977
Name: spxB
Funciton: Pyruvate oxidase (EC 1.2.3.3)
spxB
Pyruvate oxidase (EC 1.2.3.3)

Position: -76
Score: 5.1
Sequence: ATGGAAGCGTTTTCAA
Locus tag: LEUM_0795
Name: rbsR
Funciton: Ribose operon transcriptional regulator, LacI family
Locus tag: LEUM_0794
Name: rbsK
Funciton: Ribokinase (EC 2.7.1.15)
Locus tag: LEUM_0793
Name: rpiA
Funciton: Ribose 5-phosphate isomerase A (EC 5.3.1.6)
rbsR
Ribose operon transcriptional regulator, LacI family
rbsK
Ribokinase (EC 2.7.1.15)
rpiA
Ribose 5-phosphate isomerase A (EC 5.3.1.6)

Position: -53
Score: 5.1
Sequence: ATGAAAGCGCTTACTA
Locus tag: LEUM_0880
Name: lacS
Funciton: Lactose and galactose permease
lacS
Lactose and galactose permease

Position: -92
Score: 4.3
Sequence: AAGTAAACGTTTACTG
Position: -60
Score: 4.2
Sequence: TTGTAAACGTTTACGC
Locus tag: LEUM_0828
Name: nplT
Funciton: Neopullulanase (EC 3.2.1.135)
Locus tag: LEUM_0827
Name: malT2
Funciton: Predicted maltose/maltodextrin permease
nplT
Neopullulanase (EC 3.2.1.135)
malT2
Predicted maltose/maltodextrin permease

Position: -100
Score: 4.7
Sequence: ATGTAAACGGTAACAA
Position: -75
Score: 5.4
Sequence: TTGAAAGCGTTTACAA
Locus tag: LEUM_1768
Name: manL
Funciton: Mannose-specific PTS system, IIAB component (EC 2.7.1.69)
Locus tag: LEUM_1767
Name: manM
Funciton: Mannose-specific PTS system, IIC component (EC 2.7.1.69)
Locus tag: LEUM_1766
Name: manN
Funciton: Mannose-specific PTS system, IID component (EC 2.7.1.69)
Locus tag: LEUM_1765
Name: manO
Funciton: Predicted regulator of the mannose operon, ManO
manL
Mannose-specific PTS system, IIAB component (EC 2.7.1.69)
manM
Mannose-specific PTS system, IIC component (EC 2.7.1.69)
manN
Mannose-specific PTS system, IID component (EC 2.7.1.69)
manO
Predicted regulator of the mannose operon, ManO

Position: -37
Score: 5
Sequence: TTGTAACCGATTTCAT
Locus tag: LEUM_0355
Name: pgi
Funciton: Glucose-6-phosphate isomerase (EC 5.3.1.9)
pgi
Glucose-6-phosphate isomerase (EC 5.3.1.9)

Position: -72
Score: 4.8
Sequence: ATGTAAGCGGTTACTT
Locus tag: LEUM_0898
Name: malT2
Funciton: Predicted maltose/maltodextrin permease
Locus tag: LEUM_0899
Name: nplT
Funciton: Neopullulanase (EC 3.2.1.135)
malT2
Predicted maltose/maltodextrin permease
nplT
Neopullulanase (EC 3.2.1.135)

Position: -16
Score: 3.8
Sequence: AAGAAAGAGGTTAAAA
Locus tag: LEUM_1919
Name: adhA
Funciton: Alcohol dehydrogenase, Zn-dependent (EC 1.1.1.1)
adhA
Alcohol dehydrogenase, Zn-dependent (EC 1.1.1.1)

Position: -62
Score: 4.5
Sequence: TTGTGAACGTTTTCAT
Locus tag: LEUM_1571
Name: ndk
Funciton: Nucleoside diphosphate kinase (EC 2.7.4.6)
ndk
Nucleoside diphosphate kinase (EC 2.7.4.6)

Position: -104
Score: 5
Sequence: TTGTAAGCGTTTCCAA
Locus tag: LEUM_0852
Name: araA
Funciton: L-arabinose isomerase (EC 5.3.1.4)
Locus tag: LEUM_0853
Name: araE
Funciton: Arabinose-proton symporter
Locus tag: LEUM_0854
Name: araB
Funciton: Ribulokinase (EC 2.7.1.16)
Locus tag: LEUM_0855
Name: araD
Funciton: L-ribulose-5-phosphate 4-epimerase (EC 5.1.3.4)
araA
L-arabinose isomerase (EC 5.3.1.4)
araE
Arabinose-proton symporter
araB
Ribulokinase (EC 2.7.1.16)
araD
L-ribulose-5-phosphate 4-epimerase (EC 5.1.3.4)

Position: 29
Score: 4.4
Sequence: GAGAAAACGCTTAAAA
Locus tag: LEUM_2039
Name: LEUM_2039
Funciton: Predicted transcriptional regulator of FeS culster biosynthesis, XRE family
Locus tag: LEUM_2038
Name: sufC
Funciton: Iron-sulfur cluster assembly ATPase protein
Locus tag: LEUM_2037
Name: sufD
Funciton: Iron-sulfur cluster assembly protein
Locus tag: LEUM_2036
Name: sufS
Funciton: Cysteine desulfurase (EC 2.8.1.7), SufS subfamily
Locus tag: LEUM_2035
Name: sufA
Funciton: Fe-S cluster formation protein, NifU-like
Locus tag: LEUM_2034
Name: sufB
Funciton: Fe-S cluster assembly ABC-type transport system, permease component
LEUM_2039
Predicted transcriptional regulator of FeS culster biosynthesis, XRE family
sufC
Iron-sulfur cluster assembly ATPase protein
sufD
Iron-sulfur cluster assembly protein
sufS
Cysteine desulfurase (EC 2.8.1.7), SufS subfamily
sufA
Fe-S cluster formation protein, NifU-like
sufB
Fe-S cluster assembly ABC-type transport system, permease component

Position: -147
Score: 4.6
Sequence: ATGATAGCGCTTCCAA
Locus tag: LEUM_1311
Name: galM
Funciton: Aldose 1-epimerase (EC 5.1.3.3); Galactose mutarotase and related enzymes
galM
Aldose 1-epimerase (EC 5.1.3.3); Galactose mutarotase and related enzymes

Position: -85
Score: 5
Sequence: ATGCAAGCGCTTACAT
Locus tag: LEUM_1273
Name: fmpA
Funciton: Predicted mannose specific PTS system, IIA component
Locus tag: LEUM_1272
Name: fmpB
Funciton: Predicted mannose specific PTS system, IIB component
Locus tag: LEUM_1271
Name: fmpC
Funciton: Predicted mannose specific PTS system, IIC component
Locus tag: LEUM_1270
Name: fmpD
Funciton: Predicted mannose specific PTS system,
Locus tag: LEUM_1269
Name: fmpE
Funciton: Predicted mannose specific PTS system, putative EII component
fmpA
Predicted mannose specific PTS system, IIA component
fmpB
Predicted mannose specific PTS system, IIB component
fmpC
Predicted mannose specific PTS system, IIC component
fmpD
Predicted mannose specific PTS system,
fmpE
Predicted mannose specific PTS system, putative EII component

Position: -169
Score: 4.6
Sequence: GTGAAACCGTTATCAT
Locus tag: LEUM_0775
Name: pyk
Funciton: Pyruvate kinase (EC 2.7.1.40)
pyk
Pyruvate kinase (EC 2.7.1.40)

Position: -80
Score: 4.5
Sequence: CTGTAAGCGCTTCCAT
Locus tag: LEUM_1064
Name: lacZ
Funciton: Beta-galactosidase (EC 3.2.1.23)
Locus tag: LEUM_1065
Name: lacS
Funciton: Lactose and galactose permease, GPH translocator family
lacZ
Beta-galactosidase (EC 3.2.1.23)
lacS
Lactose and galactose permease, GPH translocator family

Position: -124
Score: 4.9
Sequence: TTGCAAACGCTTACAA
Position: -102
Score: 4.2
Sequence: TTATAAGTGTTTTCAT
Locus tag: LEUM_0543
Name: pepQ
Funciton: Xaa-Pro dipeptidase (EC 3.4.13.9)
pepQ
Xaa-Pro dipeptidase (EC 3.4.13.9)

Position: -157
Score: 5.3
Sequence: ATGTAAACGTTTTCAT
Position: -63
Score: 4.7
Sequence: TTGTAAGCGCTTTGAT
Locus tag: LEUM_1780
Name: ptsH
Funciton: Phosphotransferase system, HPr-related protein
Locus tag: LEUM_1779
Name: ptsI
Funciton: Phosphoenolpyruvate-protein kinase, PTS system component (EC 2.7.3.9)
ptsH
Phosphotransferase system, HPr-related protein
ptsI
Phosphoenolpyruvate-protein kinase, PTS system component (EC 2.7.3.9)

Position: -76
Score: 5.1
Sequence: TTGGAAGCGTTTACAA
Locus tag: LEUM_0499
Name: LVIS_0438
Funciton: Hypothetical protein
Locus tag: LEUM_0500
Name: LVIS_0439
Funciton: Sugar phosphate isomerase/epimerase
Locus tag: LEUM_0501
Name: LVIS_0440
Funciton: H+/gluconate symporter related permease
Locus tag: LEUM_0502
Name: LVIS_0441
Funciton: 2-dehydro-3-deoxygluconokinase
LVIS_0438
Hypothetical protein
LVIS_0439
Sugar phosphate isomerase/epimerase
LVIS_0440
H+/gluconate symporter related permease
LVIS_0441
2-dehydro-3-deoxygluconokinase

Position: -77
Score: 4.8
Sequence: AGGTAAGCGTTTACAT
Locus tag: LEUM_1316
Name: null
Funciton: Beta-galactosidase (EC 3.2.1.23)
Locus tag: LEUM_1315
Name: yghZ
Funciton: Predicted oxidoreductase, aryl-alcohol dehydrogenase related
Beta-galactosidase (EC 3.2.1.23)
yghZ
Predicted oxidoreductase, aryl-alcohol dehydrogenase related

Position: -31
Score: 4.9
Sequence: GTGTAAGCGGTTACAA
Locus tag: LEUM_0736
Name: lplA1
Funciton: Lipoate-protein ligase A
Locus tag: LEUM_0737
Name: pdhA
Funciton: Dihydrolipoamide dehydrogenase complex (EC 1.8.1.4), E1 component alpha-subunit
Locus tag: LEUM_0738
Name: pdhB
Funciton: Dihydrolipoamide dehydrogenase complex (EC 1.8.1.4), E1 component beta-subunit
Locus tag: LEUM_0739
Name: pdhC
Funciton: Dihydrolipoamide dehydrogenase complex (EC 1.8.1.4), E2 component
Locus tag: LEUM_0740
Name: pdhD
Funciton: Dihydrolipoamide dehydrogenase complex (EC 1.8.1.4), E3 component
lplA1
Lipoate-protein ligase A
pdhA
Dihydrolipoamide dehydrogenase complex (EC 1.8.1.4), E1 component alpha-subunit
pdhB
Dihydrolipoamide dehydrogenase complex (EC 1.8.1.4), E1 component beta-subunit
pdhC
Dihydrolipoamide dehydrogenase complex (EC 1.8.1.4), E2 component
pdhD
Dihydrolipoamide dehydrogenase complex (EC 1.8.1.4), E3 component

Position: -86
Score: 5.1
Sequence: TTGTAACCGTTTACAT
Locus tag: LEUM_0507
Name: treP
Funciton: Trehalose-specific PTS system, EIIABC component (EC 2.7.1.69)
Locus tag: LEUM_0508
Name: treP
Funciton: Trehalose-specific PTS system, EIIABC component (EC 2.7.1.69)
Locus tag: LEUM_0509
Name: treA
Funciton: Trehalose-6-phosphate hydrolase (EC 3.2.1.93)
treP
Trehalose-specific PTS system, EIIABC component (EC 2.7.1.69)
treP
Trehalose-specific PTS system, EIIABC component (EC 2.7.1.69)
treA
Trehalose-6-phosphate hydrolase (EC 3.2.1.93)

Position: -114
Score: 4.4
Sequence: ATGAAAACACTTATAA
Position: -92
Score: 4.9
Sequence: TTGTAAGCGTTTGCAA
Locus tag: LEUM_0544
Name: ccpA
Funciton: Carbon catabolism global transcriptional regulator CcpA, LacI family
ccpA
Carbon catabolism global transcriptional regulator CcpA, LacI family

Position: -140
Score: 4.6
Sequence: ATATAAACGGTTACAT
Locus tag: LEUM_0994
Name: malT
Funciton: Predicted maltose/maltodextrin permease
Locus tag: LEUM_0995
Name: mapA
Funciton: Maltose phosphorylase (EC 2.4.1.8) / Trehalose phosphorylase (EC 2.4.1.64)
Locus tag: LEUM_0996
Name: galM
Funciton: Aldose 1-epimerase
Locus tag: LEUM_0997
Name: pgmB
Funciton: Beta-phosphoglucomutase (EC 5.4.2.6)
malT
Predicted maltose/maltodextrin permease
mapA
Maltose phosphorylase (EC 2.4.1.8) / Trehalose phosphorylase (EC 2.4.1.64)
galM
Aldose 1-epimerase
pgmB
Beta-phosphoglucomutase (EC 5.4.2.6)

Position: -41
Score: 5
Sequence: ATGTAAACGGTTACAA
Locus tag: LEUM_0893
Name: malT
Funciton: Predicted maltose/maltodextrin permease
Locus tag: LEUM_0894
Name: mapA
Funciton: Maltose phosphorylase (EC 2.4.1.8) / Trehalose phosphorylase (EC 2.4.1.64)
Locus tag: LEUM_0895
Name: pgmB
Funciton: Beta-phosphoglucomutase (EC 5.4.2.6)
malT
Predicted maltose/maltodextrin permease
mapA
Maltose phosphorylase (EC 2.4.1.8) / Trehalose phosphorylase (EC 2.4.1.64)
pgmB
Beta-phosphoglucomutase (EC 5.4.2.6)

Position: -53
Score: 4.9
Sequence: ATGTAAGCGCATACAT
Position: -19
Score: 4.1
Sequence: TAGAAAGGGTTTAAAT
Locus tag: LEUM_1998
Name: ulaG
Funciton: Probable L-ascorbate-6-phosphate lactonase UlaG (EC 3.1.1.-) (L-ascorbate utilization protein G)
Locus tag: LEUM_1997
Name: ulaC
Funciton: Ascorbate-specific PTS system, EIIA component (EC 2.7.1.-)
Locus tag: LEUM_1996
Name: ulaA
Funciton: Ascorbate-specific PTS system, EIIC component
Locus tag: LEUM_1995
Name: ulaB
Funciton: Ascorbate-specific PTS system, EIIB component (EC 2.7.1.69)
Locus tag: LEUM_1994
Name: ulaD
Funciton: 3-keto-L-gulonate 6-phosphate decarboxylase (EC 4.1.1.85)
ulaG
Probable L-ascorbate-6-phosphate lactonase UlaG (EC 3.1.1.-) (L-ascorbate utilization protein G)
ulaC
Ascorbate-specific PTS system, EIIA component (EC 2.7.1.-)
ulaA
Ascorbate-specific PTS system, EIIC component
ulaB
Ascorbate-specific PTS system, EIIB component (EC 2.7.1.69)
ulaD
3-keto-L-gulonate 6-phosphate decarboxylase (EC 4.1.1.85)

Position: -83
Score: 5
Sequence: ATGAAAGCGTATACAA
Locus tag: LEUM_0130
Name: xylA
Funciton: Xylose isomerase (EC 5.3.1.5)
Locus tag: LEUM_0131
Name: xylB
Funciton: Xylulose kinase (EC 2.7.1.17)
xylA
Xylose isomerase (EC 5.3.1.5)
xylB
Xylulose kinase (EC 2.7.1.17)

Position: -77
Score: 4.7
Sequence: AAGTAACCGTTTACAT
Locus tag: LEUM_0882
Name: melA
Funciton: Alpha-galactosidase (EC 3.2.1.22)
Locus tag: LEUM_0883
Name: galK
Funciton: Galactokinase (EC 2.7.1.6)
Locus tag: LEUM_0884
Name: galT
Funciton: Galactose-1-phosphate uridylyltransferase (EC 2.7.7.10)
melA
Alpha-galactosidase (EC 3.2.1.22)
galK
Galactokinase (EC 2.7.1.6)
galT
Galactose-1-phosphate uridylyltransferase (EC 2.7.7.10)

Position: -66
Score: 5.3
Sequence: TTGTAAACGCTTACAT
Locus tag: LEUM_1314
Name: lacS
Funciton: Lactose and galactose permease, GPH translocator family
Locus tag: LEUM_1313
Name: galK
Funciton: Galactokinase (EC 2.7.1.6)
lacS
Lactose and galactose permease, GPH translocator family
galK
Galactokinase (EC 2.7.1.6)

Position: -292
Score: 3.9
Sequence: TTTCAAGCGCTTCAAT
Locus tag: LEUM_1392
Name: glpF2
Funciton: Glycerol uptake facilitator protein
glpF2
Glycerol uptake facilitator protein

Position: -137
Score: 4.1
Sequence: ATGATAATGTTTTCAT
Position: -54
Score: 4.4
Sequence: GTGGAACCGGTTACAA
Locus tag: LEUM_0383
Name: scrT
Funciton: Predicted sucrose permease
Locus tag: LEUM_0384
Name: scrP
Funciton: Sucrose phosphorylase (EC 2.4.1.7)
scrT
Predicted sucrose permease
scrP
Sucrose phosphorylase (EC 2.4.1.7)
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Regulated Genes [ Tab delimited format ] DOWNLOAD
Regulatory Sites [ FASTA format ] DOWNLOAD