Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 4.0 --

Regulon of CcpA in Lactobacillus rhamnosus GG

Properties
Regulator type: Transcription factor
TF locus tag: LGG_00793
Regulator family: LacI
Regulation mode:
Biological process: Carbon catabolism
Effector: HPr, phosphocarrier protein; Fructose-1,6-bisphosphate
Regulog: CcpA - Lactobacillaceae
Statistics of regulated genes:
- Genes 68
- Operons 29
Visualization:
Allows to visualize regulon content in the context of metabolic pathways
Built upon 561 sites [see more]
Member of regulog collections
Regulated operons
Locus Tag Name Function

Position: -95
Score: 4
Sequence: AGTAAAACGCTTGCAT
Locus tag: LGG_00793
Name: ccpA
Funciton: Carbon catabolism global transcriptional regulator CcpA, LacI family
ccpA
Carbon catabolism global transcriptional regulator CcpA, LacI family

Position: -197
Score: 4
Sequence: CCGAAAGCGGTTACAA
Locus tag: LGG_02027
Name: glgB
Funciton: 1,4-alpha-glucan (glycogen) branching enzyme, GH-13-type (EC 2.4.1.18)
Locus tag: LGG_02026
Name: glgC
Funciton: Glucose-1-phosphate adenylyltransferase (EC 2.7.7.27)
Locus tag: LGG_02025
Name: glgD
Funciton: Glucose-1-phosphate adenylyltransferase (EC 2.7.7.27)
Locus tag: LGG_02024
Name: glgA
Funciton: Glycogen synthase, ADP-glucose transglucosylase (EC 2.4.1.21)
Locus tag: LGG_02023
Name: glgP
Funciton: Glycogen phosphorylase (EC 2.4.1.1)
Locus tag: LGG_02022
Name: amy1
Funciton: Neopullulanase (EC 3.2.1.135)
glgB
1,4-alpha-glucan (glycogen) branching enzyme, GH-13-type (EC 2.4.1.18)
glgC
Glucose-1-phosphate adenylyltransferase (EC 2.7.7.27)
glgD
Glucose-1-phosphate adenylyltransferase (EC 2.7.7.27)
glgA
Glycogen synthase, ADP-glucose transglucosylase (EC 2.4.1.21)
glgP
Glycogen phosphorylase (EC 2.4.1.1)
amy1
Neopullulanase (EC 3.2.1.135)

Position: -87
Score: 4.7
Sequence: ATGAAAGCGCTTATTA
Locus tag: LGG_02685
Name: fucI
Funciton: L-fucose isomerase (EC 5.3.1.25)
Locus tag: LGG_02684
Name: fucK
Funciton: L-fuculokinase (EC 2.7.1.51)
Locus tag: LGG_02683
Name: fucT
Funciton: Predicted fucose transporter
Locus tag: LGG_02682
Name: fucU
Funciton: L-fucose mutarotase (EC 5.1.3.n2)
fucI
L-fucose isomerase (EC 5.3.1.25)
fucK
L-fuculokinase (EC 2.7.1.51)
fucT
Predicted fucose transporter
fucU
L-fucose mutarotase (EC 5.1.3.n2)

Position: -58
Score: 4.5
Sequence: TTGCAAGCGCTTACGA
Locus tag: LGG_02680
Name: fucR
Funciton: L-fucose utilization transcriptional regulator FucR, DeoR family
fucR
L-fucose utilization transcriptional regulator FucR, DeoR family

Position: -136
Score: 4.6
Sequence: ATTAAAGCGCTTTCCT
Position: -89
Score: 4.1
Sequence: GTGAAAGGGTTTGCAT
Locus tag: LGG_01836
Name: spxB
Funciton: Pyruvate oxidase (EC 1.2.3.3)
spxB
Pyruvate oxidase (EC 1.2.3.3)

Position: -51
Score: 5.1
Sequence: TAGAAAACGTTTTCAT
Locus tag: LGG_00644
Name: glpK
Funciton: Glycerol kinase (EC 2.7.1.30)
Locus tag: LGG_00643
Name: glpD
Funciton: Alpha-glycerophosphate oxidase (EC 1.1.3.21)
Locus tag: LGG_00642
Name: glpF
Funciton: Glycerol uptake facilitator protein
glpK
Glycerol kinase (EC 2.7.1.30)
glpD
Alpha-glycerophosphate oxidase (EC 1.1.3.21)
glpF
Glycerol uptake facilitator protein

Position: -89
Score: 4.5
Sequence: TTGACAGCGCTTCCAT
Locus tag: LGG_00372
Name: rbsR
Funciton: Ribose operon transcriptional regulator, LacI family
rbsR
Ribose operon transcriptional regulator, LacI family

Position: -91
Score: 4.2
Sequence: CTGAAAGCGCTTGTAA
Locus tag: LGG_02823
Name: pts20B
Funciton: PTS system, cellobiose-specific IIB component (EC 2.7.1.69)
Locus tag: LGG_02824
Name: pts20A
Funciton: PTS system, cellobiose-specific IIA component (EC 2.7.1.69)
pts20B
PTS system, cellobiose-specific IIB component (EC 2.7.1.69)
pts20A
PTS system, cellobiose-specific IIA component (EC 2.7.1.69)

Position: -158
Score: 4.1
Sequence: ATGAAAAGGGTTTCCA
Locus tag: LGG_01221
Name: pnuC
Funciton: NrdR-regulated deoxyribonucleotide transporter; Nicotinamide mononucleotide transporter
pnuC
NrdR-regulated deoxyribonucleotide transporter; Nicotinamide mononucleotide transporter

Position: -65
Score: 4.5
Sequence: TTGTCAGCGATTACAT
Locus tag: LGG_02912
Name: mtlA
Funciton: Mannitol-specific PTS system, IIBC component (EC 2.7.1.69)
Locus tag: LGG_02911
Name: mtlR
Funciton: Mannitol operon antiterminator, BglG family
Locus tag: LGG_02910
Name: mtlF
Funciton: Mannitol-specific PTS system, mannitol-specific IIA component (EC 2.7.1.69)
Locus tag: LGG_02909
Name: mtlD
Funciton: Mannitol-1-phosphate 5-dehydrogenase (EC 1.1.1.17)
mtlA
Mannitol-specific PTS system, IIBC component (EC 2.7.1.69)
mtlR
Mannitol operon antiterminator, BglG family
mtlF
Mannitol-specific PTS system, mannitol-specific IIA component (EC 2.7.1.69)
mtlD
Mannitol-1-phosphate 5-dehydrogenase (EC 1.1.1.17)

Position: -64
Score: 4.8
Sequence: ATGTAAGCGGTTAAAT
Locus tag: LGG_02691
Name: rhaY
Funciton: Predicted L-rhamnose permease RhaY
Locus tag: LGG_02690
Name: rhaB
Funciton: Rhamnulokinase (EC 2.7.1.5)
Locus tag: LGG_02689
Name: rhaU
Funciton: L-rhamnose 1-epimerase (EC 5.1.3.-)
Locus tag: LGG_02688
Name: rhaA
Funciton: L-rhamnose isomerase (EC 5.3.1.14)
Locus tag: LGG_02687
Name: rhaD
Funciton: Rhamnulose-1-phosphate aldolase (EC 4.1.2.19)
rhaY
Predicted L-rhamnose permease RhaY
rhaB
Rhamnulokinase (EC 2.7.1.5)
rhaU
L-rhamnose 1-epimerase (EC 5.1.3.-)
rhaA
L-rhamnose isomerase (EC 5.3.1.14)
rhaD
Rhamnulose-1-phosphate aldolase (EC 4.1.2.19)

Position: -77
Score: 4.8
Sequence: ATGAATGCGGTTACAA
Locus tag: LGG_02762
Name: LBA0143
Funciton: Maltodextrin glucosidase (EC 3.2.1.20); Alpha-glucosidase, family 31 of glycosyl hydrolase
LBA0143
Maltodextrin glucosidase (EC 3.2.1.20); Alpha-glucosidase, family 31 of glycosyl hydrolase

Position: -150
Score: 4.1
Sequence: TCGAAATCGCTTTCTT
Locus tag: LGG_01479
Name: lplA1
Funciton: Lipoate-protein ligase A
lplA1
Lipoate-protein ligase A

Position: -111
Score: 4.2
Sequence: AATAAAACGCTTGCAA
Locus tag: LGG_01320
Name: pdhA
Funciton: Dihydrolipoamide dehydrogenase complex (EC 1.8.1.4), E1 component alpha-subunit
Locus tag: LGG_01321
Name: pdhB
Funciton: Dihydrolipoamide dehydrogenase complex (EC 1.8.1.4), E1 component beta-subunit
Locus tag: LGG_01322
Name: pdhC
Funciton: Dihydrolipoamide dehydrogenase complex (EC 1.8.1.4), E2 component
Locus tag: LGG_01323
Name: pdhD
Funciton: Dihydrolipoamide dehydrogenase complex (EC 1.8.1.4), E3 component
pdhA
Dihydrolipoamide dehydrogenase complex (EC 1.8.1.4), E1 component alpha-subunit
pdhB
Dihydrolipoamide dehydrogenase complex (EC 1.8.1.4), E1 component beta-subunit
pdhC
Dihydrolipoamide dehydrogenase complex (EC 1.8.1.4), E2 component
pdhD
Dihydrolipoamide dehydrogenase complex (EC 1.8.1.4), E3 component

Position: -27
Score: 4.3
Sequence: GTGAAAACGGTTACTG
Locus tag: LGG_00601
Name: treR
Funciton: Trehalose utilization transcriptional regulator TreR, GntR family
Locus tag: LGG_00602
Name: treA
Funciton: Trehalose-6-phosphate hydrolase (EC 3.2.1.93)
Locus tag: LGG_00603
Name: treP
Funciton: Trehalose-specific PTS system, EIIABC component (EC 2.7.1.69)
treR
Trehalose utilization transcriptional regulator TreR, GntR family
treA
Trehalose-6-phosphate hydrolase (EC 3.2.1.93)
treP
Trehalose-specific PTS system, EIIABC component (EC 2.7.1.69)

Position: -85
Score: 4.4
Sequence: GTGAAAGCCTTTTCAA
Locus tag: LGG_01876
Name: pck
Funciton: Phosphoenolpyruvate carboxykinase (EC 4.1.1.49)
pck
Phosphoenolpyruvate carboxykinase (EC 4.1.1.49)

Position: -115
Score: 4.5
Sequence: GAGAAAGCGCTTATAA
Locus tag: LGG_02307
Name: cad
Funciton: Predicted pheromone precursor lipoprotein, related to Cad
cad
Predicted pheromone precursor lipoprotein, related to Cad

Position: -170
Score: 4.7
Sequence: TTAAATGCGCTTTCAT
Locus tag: LGG_02679
Name: lhv_0924
Funciton: Predicted transcriptional regulator, GntR family
lhv_0924
Predicted transcriptional regulator, GntR family

Position: -79
Score: 4.4
Sequence: TTGAAACCGTTTTCGG
Locus tag: LGG_02071
Name: lulA
Funciton: Lactate utilization protein A
Locus tag: LGG_02070
Name: lulC
Funciton: Lactate utilization protein C
Locus tag: LGG_02069
Name: lulB
Funciton: Lactate utilization protein B
lulA
Lactate utilization protein A
lulC
Lactate utilization protein C
lulB
Lactate utilization protein B

Position: -82
Score: 4.8
Sequence: TTGAAACCGTATACAA
Locus tag: LGG_02032
Name: fbp
Funciton: Fructose-1,6-bisphosphatase, Bacillus type (EC 3.1.3.11)
fbp
Fructose-1,6-bisphosphatase, Bacillus type (EC 3.1.3.11)

Position: -193
Score: 4.4
Sequence: TTGCAAGCGTTTACGT
Locus tag: LGG_02523
Name: ldh
Funciton: L-lactate dehydrogenase (EC 1.1.1.27)
ldh
L-lactate dehydrogenase (EC 1.1.1.27)

Position: -194
Score: 4.7
Sequence: TTGTAAGCGGTTTCTG
Locus tag: LGG_00277
Name: gntP
Funciton: H+/gluconate symporter related permease
gntP
H+/gluconate symporter related permease

Position: -106
Score: 4.7
Sequence: TTGAAAGCGCTATCGT
Locus tag: LGG_00704
Name: yxjF
Funciton: Predicted short-chain alcohol dehydrogenase
Locus tag: LGG_00705
Name: adc
Funciton: Probable acetoacetate decarboxylase
Locus tag: LGG_00706
Name: ydgI
Funciton: Putative NAD(P)H nitroreductase
yxjF
Predicted short-chain alcohol dehydrogenase
adc
Probable acetoacetate decarboxylase
ydgI
Putative NAD(P)H nitroreductase

Position: -36
Score: 4.7
Sequence: ATGAATGCGTTTTCTT
Locus tag: LGG_02577
Name: lacX
Funciton: Aldose 1-epimerase
lacX
Aldose 1-epimerase

Position: -64
Score: 4.7
Sequence: ATAAAAACGGTTACAA
Locus tag: LGG_00653
Name: galK
Funciton: Galactokinase (EC 2.7.1.6)
Locus tag: LGG_00654
Name: galE
Funciton: UDP-glucose 4-epimerase (EC 5.1.3.2)
Locus tag: LGG_00655
Name: galT
Funciton: Galactose-1-phosphate uridylyltransferase (EC 2.7.7.10)
Locus tag: LGG_00656
Name: galR
Funciton: Galactose utilization transcriptional regulator GalR, LacI family
Locus tag: LGG_00657
Name: galM
Funciton: Aldose 1-epimerase (EC 5.1.3.3)
galK
Galactokinase (EC 2.7.1.6)
galE
UDP-glucose 4-epimerase (EC 5.1.3.2)
galT
Galactose-1-phosphate uridylyltransferase (EC 2.7.7.10)
galR
Galactose utilization transcriptional regulator GalR, LacI family
galM
Aldose 1-epimerase (EC 5.1.3.3)

Position: -100
Score: 3.9
Sequence: TTGAGCGCGTTTTCAA
Locus tag: LGG_00921
Name: pgm
Funciton: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I, II & III
pgm
phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I, II & III

Position: -68
Score: 4.7
Sequence: TTGTAAGCGCAATCAA
Locus tag: LGG_02733
Name: ulaG
Funciton: Probable L-ascorbate-6-phosphate lactonase UlaG (EC 3.1.1.-) (L-ascorbate utilization protein G)
Locus tag: LGG_02732
Name: ulaC
Funciton: Ascorbate-specific PTS system, EIIA component (EC 2.7.1.-)
Locus tag: LGG_02731
Name: ulaA
Funciton: Ascorbate-specific PTS system, EIIC component
Locus tag: LGG_02730
Name: ulaB
Funciton: Ascorbate-specific PTS system, EIIB component (EC 2.7.1.69)
ulaG
Probable L-ascorbate-6-phosphate lactonase UlaG (EC 3.1.1.-) (L-ascorbate utilization protein G)
ulaC
Ascorbate-specific PTS system, EIIA component (EC 2.7.1.-)
ulaA
Ascorbate-specific PTS system, EIIC component
ulaB
Ascorbate-specific PTS system, EIIB component (EC 2.7.1.69)

Position: -94
Score: 4.5
Sequence: ATGAAATCGGATACAT
Locus tag: LGG_00606
Name: ldh
Funciton: L-lactate dehydrogenase 1 (L-LDH 1)
ldh
L-lactate dehydrogenase 1 (L-LDH 1)

Position: -47
Score: 4.4
Sequence: AAGAAAACGCTACCAT
Locus tag: LGG_02722
Name: sorD
Funciton: Sorbitol-6-phosphate 2-dehydrogenase (EC 1.1.1.140)
Locus tag: LGG_02721
Name: srlM
Funciton: Sorbitol operon transcription regulator
Locus tag: LGG_02720
Name: srlR
Funciton: Glucitol operon activator protein
Locus tag: LGG_02719
Name: srlA
Funciton: Glucitol/sorbitol-specific PTS system, IIC component (EC 2.7.1.69)
Locus tag: LGG_02718
Name: srlE
Funciton: Glucitol/sorbitol-specific PTS system, IIBC components (EC 2.7.1.69)
Locus tag: LGG_02717
Name: srlB
Funciton: Glucitol/sorbitol-specific PTS system, IIA component (EC 2.7.1.69)
sorD
Sorbitol-6-phosphate 2-dehydrogenase (EC 1.1.1.140)
srlM
Sorbitol operon transcription regulator
srlR
Glucitol operon activator protein
srlA
Glucitol/sorbitol-specific PTS system, IIC component (EC 2.7.1.69)
srlE
Glucitol/sorbitol-specific PTS system, IIBC components (EC 2.7.1.69)
srlB
Glucitol/sorbitol-specific PTS system, IIA component (EC 2.7.1.69)
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