Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 4.0 --

Regulon of CcpA in Lactobacillus reuteri JCM 1112

Properties
Regulator type: Transcription factor
TF locus tag: LAR_0536
Regulator family: LacI
Regulation mode:
Biological process: Carbon catabolism
Effector: HPr, phosphocarrier protein; Fructose-1,6-bisphosphate
Regulog: CcpA - Lactobacillaceae
Statistics of regulated genes:
- Genes 53
- Operons 29
Visualization:
Allows to visualize regulon content in the context of metabolic pathways
Built upon 561 sites [see more]
Member of regulog collections
Regulated operons
Locus Tag Name Function

Position: -135
Score: 4.4
Sequence: TGAAAAGCGATTTCAA
Position: -76
Score: 4.5
Sequence: TTGTAATCACTTTCAA
Locus tag: LAR_0399
Name: rbsK
Funciton: Ribokinase (EC 2.7.1.15)
Locus tag: LAR_0400
Name: rbsD
Funciton: Ribose ABC transport system, high affinity permease RbsD (TC 3.A.1.2.1)
Locus tag: LAR_0401
Name: rbsP
Funciton: Predicted ribose permease
rbsK
Ribokinase (EC 2.7.1.15)
rbsD
Ribose ABC transport system, high affinity permease RbsD (TC 3.A.1.2.1)
rbsP
Predicted ribose permease

Position: -44
Score: 4.6
Sequence: GAGTAACCGTTTTCAT
Locus tag: LAR_1512
Name: coaA
Funciton: Pantothenate kinase (EC 2.7.1.33)
coaA
Pantothenate kinase (EC 2.7.1.33)

Position: -66
Score: 4.5
Sequence: ACGAAAACGTTTACAT
Locus tag: LAR_0972
Name: agl3
Funciton: Alpha-glucosidase (EC 3.2.1.20)
agl3
Alpha-glucosidase (EC 3.2.1.20)

Position: -130
Score: 4.9
Sequence: ATGTAATCGTTTACAT
Locus tag: LAR_0078
Name: nplT
Funciton: Neopullulanase (EC 3.2.1.135)
Locus tag: LAR_0079
Name: melB2
Funciton: Sugar transport protein
nplT
Neopullulanase (EC 3.2.1.135)
melB2
Sugar transport protein

Position: -63
Score: 4.7
Sequence: ATGAAAGCGCGTTCAT
Locus tag: LAR_0467
Name: araE
Funciton: Arabinose-proton symporter
Locus tag: LAR_0468
Name: araB
Funciton: Ribulokinase (EC 2.7.1.16)
Locus tag: LAR_0469
Name: araD
Funciton: L-ribulose-5-phosphate 4-epimerase (EC 5.1.3.4)
Locus tag: LAR_0470
Name: araA
Funciton: L-arabinose isomerase (EC 5.3.1.4)
araE
Arabinose-proton symporter
araB
Ribulokinase (EC 2.7.1.16)
araD
L-ribulose-5-phosphate 4-epimerase (EC 5.1.3.4)
araA
L-arabinose isomerase (EC 5.3.1.4)

Position: -89
Score: 4.2
Sequence: GTGCAAGCGGTTGCAA
Position: -52
Score: 4.6
Sequence: ATGTAAGCGTAATCAT
Locus tag: LAR_1508
Name: malT2
Funciton: Predicted maltose/maltodextrin permease
Locus tag: LAR_1507
Name: nplT
Funciton: Neopullulanase (EC 3.2.1.135)
malT2
Predicted maltose/maltodextrin permease
nplT
Neopullulanase (EC 3.2.1.135)

Position: -74
Score: 4.6
Sequence: CTAAAAACGCTTTCAA
Locus tag: LAR_0192
Name: ndk
Funciton: Nucleoside diphosphate kinase (EC 2.7.4.6)
ndk
Nucleoside diphosphate kinase (EC 2.7.4.6)

Position: -101
Score: 4.4
Sequence: GTGAAAACGAATACAA
Locus tag: LAR_0851
Name: lrgA
Funciton: Antiholin-like protein LrgA
Locus tag: LAR_0852
Name: lrgB
Funciton: LrgA-associated membrane protein LrgB
lrgA
Antiholin-like protein LrgA
lrgB
LrgA-associated membrane protein LrgB

Position: -33
Score: 4.4
Sequence: GTAAAAGCGCTTACTT
Locus tag: LAR_1448
Name: galM
Funciton: Aldose 1-epimerase (EC 5.1.3.3); Galactose mutarotase and related enzymes
galM
Aldose 1-epimerase (EC 5.1.3.3); Galactose mutarotase and related enzymes

Position: -115
Score: 4.6
Sequence: ATTAAATCGTTTTCAA
Locus tag: LAR_0364
Name: lulA
Funciton: Lactate utilization protein A
Locus tag: LAR_0363
Name: lulC
Funciton: Lactate utilization protein C
Locus tag: LAR_0362
Name: lulB
Funciton: Lactate utilization protein B
lulA
Lactate utilization protein A
lulC
Lactate utilization protein C
lulB
Lactate utilization protein B

Position: -139
Score: 4.4
Sequence: ATGATAGCGCTTTTTT
Locus tag: LAR_0722
Name: pyk
Funciton: Pyruvate kinase (EC 2.7.1.40)
pyk
Pyruvate kinase (EC 2.7.1.40)

Position: -39
Score: 4.4
Sequence: ATGGAATCGTATTCAA
Locus tag: LAR_0029
Name: dhaT
Funciton: 1,3-propanediol dehydrogenase (EC 1.1.1.202)
dhaT
1,3-propanediol dehydrogenase (EC 1.1.1.202)

Position: -42
Score: 4.7
Sequence: TTGTAAGCGATTACAG
Locus tag: LAR_1033
Name: lacS
Funciton: Lactose and galactose permease, GPH translocator family
Locus tag: LAR_1032
Name: lacZ
Funciton: Beta-galactosidase (EC 3.2.1.23)
lacS
Lactose and galactose permease, GPH translocator family
lacZ
Beta-galactosidase (EC 3.2.1.23)

Position: -132
Score: 4.8
Sequence: TTGTAAGCGAATTCAT
Locus tag: LAR_0310
Name: adhE
Funciton: Alcohol dehydrogenase (EC 1.1.1.1); Acetaldehyde dehydrogenase (EC 1.2.1.10)
adhE
Alcohol dehydrogenase (EC 1.1.1.1); Acetaldehyde dehydrogenase (EC 1.2.1.10)

Position: -132
Score: 4.1
Sequence: ATAAAAGGGCTTTTAT
Position: -30
Score: 4.6
Sequence: ATGTAAGCGTTTATTT
Locus tag: LAR_0033
Name: gabD
Funciton: Succinate-semialdehyde dehydrogenase [NAD] (EC 1.2.1.24); Succinate-semialdehyde dehydrogenase [NADP+] (EC 1.2.1.16)
gabD
Succinate-semialdehyde dehydrogenase [NAD] (EC 1.2.1.24); Succinate-semialdehyde dehydrogenase [NADP+] (EC 1.2.1.16)

Position: -102
Score: 4
Sequence: TATTTAACGCTTACAA
Locus tag: LAR_1256
Name: ptsH
Funciton: Phosphotransferase system, HPr-related protein
Locus tag: LAR_1255
Name: ptsI
Funciton: Phosphoenolpyruvate-protein kinase, PTS system component (EC 2.7.3.9)
ptsH
Phosphotransferase system, HPr-related protein
ptsI
Phosphoenolpyruvate-protein kinase, PTS system component (EC 2.7.3.9)

Position: -90
Score: 4.7
Sequence: ATGAAAGCGCTTGTAT
Position: -40
Score: 4.3
Sequence: AAGCAATCGCTTACAT
Locus tag: LAR_0608
Name: pdhA
Funciton: Dihydrolipoamide dehydrogenase complex (EC 1.8.1.4), E1 component alpha-subunit
Locus tag: LAR_0609
Name: pdhB
Funciton: Dihydrolipoamide dehydrogenase complex (EC 1.8.1.4), E1 component beta-subunit
Locus tag: LAR_0610
Name: pdhC
Funciton: Dihydrolipoamide dehydrogenase complex (EC 1.8.1.4), E2 component
Locus tag: LAR_0611
Name: pdhD
Funciton: Dihydrolipoamide dehydrogenase complex (EC 1.8.1.4), E3 component
pdhA
Dihydrolipoamide dehydrogenase complex (EC 1.8.1.4), E1 component alpha-subunit
pdhB
Dihydrolipoamide dehydrogenase complex (EC 1.8.1.4), E1 component beta-subunit
pdhC
Dihydrolipoamide dehydrogenase complex (EC 1.8.1.4), E2 component
pdhD
Dihydrolipoamide dehydrogenase complex (EC 1.8.1.4), E3 component

Position: -104
Score: 4.7
Sequence: TTGCAAACGCTTACTA
Locus tag: LAR_1565
Name: lplA1
Funciton: Lipoate-protein ligase A
lplA1
Lipoate-protein ligase A

Position: -53
Score: 4.4
Sequence: ATGAAAGCGCTATACT
Locus tag: LAR_0276
Name: lacL
Funciton: Beta-galactosidase large subunit (EC 3.2.1.23)
Locus tag: LAR_0277
Name: lacM
Funciton: Beta-galactosidase small subunit (EC 3.2.1.23)
lacL
Beta-galactosidase large subunit (EC 3.2.1.23)
lacM
Beta-galactosidase small subunit (EC 3.2.1.23)

Position: -65
Score: 4.6
Sequence: TTGAAGCCGCTTTCAA
Locus tag: LAR_1455
Name: arcD
Funciton: Arginine/ornithine antiporter
Locus tag: LAR_1454
Name: arcT
Funciton: Xaa-His dipeptidase (EC 3.4.13.3)
arcD
Arginine/ornithine antiporter
arcT
Xaa-His dipeptidase (EC 3.4.13.3)

Position: -149
Score: 4.8
Sequence: ATGGAAACGCTATCAT
Locus tag: LAR_0406
Name: lp_0827
Funciton: Conserved hypothetical protein
lp_0827
Conserved hypothetical protein

Position: -74
Score: 5.3
Sequence: TTGAAAACGTTTACAA
Locus tag: LAR_0083
Name: malR3
Funciton: Predicted maltose/maltodextrin utilization transcriptional regulator MalR3, LacI family
malR3
Predicted maltose/maltodextrin utilization transcriptional regulator MalR3, LacI family

Position: -125
Score: 4.5
Sequence: GTGTAATCGTTTTCTT
Position: -93
Score: 4.4
Sequence: TTGTAAGCGCTTATTG
Locus tag: LAR_1662
Name: galK
Funciton: Galactokinase (EC 2.7.1.6)
Locus tag: LAR_1661
Name: galT
Funciton: Galactose-1-phosphate uridylyltransferase (EC 2.7.7.10)
Locus tag: LAR_1660
Name: galR
Funciton: Galactose utilization transcriptional regulator GalR, LacI family
galK
Galactokinase (EC 2.7.1.6)
galT
Galactose-1-phosphate uridylyltransferase (EC 2.7.7.10)
galR
Galactose utilization transcriptional regulator GalR, LacI family

Position: -69
Score: 4.4
Sequence: TTGAAACCGACTTCAT
Locus tag: LAR_0415
Name: pgi
Funciton: Glucose-6-phosphate isomerase (EC 5.3.1.9)
pgi
Glucose-6-phosphate isomerase (EC 5.3.1.9)

Position: -50
Score: 4.7
Sequence: TAGAAAACGCATACAA
Locus tag: LAR_1640
Name: glpF2
Funciton: Glycerol uptake facilitator protein
glpF2
Glycerol uptake facilitator protein

Position: -144
Score: 4.2
Sequence: TTGTTTCCGCTTACAT
Locus tag: LAR_0419
Name: null
Funciton: Ornithine carbamoyltransferase (EC 2.1.3.3)
Locus tag: LAR_0420
Name: null
Funciton: Carbamate kinase (EC 2.7.2.2)
Ornithine carbamoyltransferase (EC 2.1.3.3)
Carbamate kinase (EC 2.7.2.2)

Position: -72
Score: 4.7
Sequence: TTGACAACGTTTACAT
Locus tag: LAR_0435
Name: arcA
Funciton: Arginine deiminase (EC 3.5.3.6)
Locus tag: LAR_0436
Name: argR
Funciton: Arginine metabolism regulator ArgR
Locus tag: LAR_0437
Name: arcD
Funciton: Arginine/ornithine antiporter ArcD
arcA
Arginine deiminase (EC 3.5.3.6)
argR
Arginine metabolism regulator ArgR
arcD
Arginine/ornithine antiporter ArcD

Position: -190
Score: 4
Sequence: AAAATAGCGTTATCAT
Position: -133
Score: 4
Sequence: ATGTAATGGATTACAA
Locus tag: LAR_1453
Name: scrT
Funciton: Predicted sucrose permease
Locus tag: LAR_1452
Name: scrP
Funciton: Sucrose phosphorylase (EC 2.4.1.7)
scrT
Predicted sucrose permease
scrP
Sucrose phosphorylase (EC 2.4.1.7)

Position: -135
Score: 4.4
Sequence: TGAAAAGCGATTTCAA
Position: -76
Score: 4.5
Sequence: TTGTAATCACTTTCAA
Locus tag: LAR_0399
Name: rbsK
Funciton: Ribokinase (EC 2.7.1.15)
Locus tag: LAR_0400
Name: rbsD
Funciton: Ribose ABC transport system, high affinity permease RbsD (TC 3.A.1.2.1)
rbsK
Ribokinase (EC 2.7.1.15)
rbsD
Ribose ABC transport system, high affinity permease RbsD (TC 3.A.1.2.1)
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Regulated Genes [ Tab delimited format ] DOWNLOAD
Regulatory Sites [ FASTA format ] DOWNLOAD