Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 4.0 --

Regulon of CcpA in Lactobacillus johnsonii NCC 533

Properties
Regulator type: Transcription factor
TF locus tag: LJ0491
Regulator family: LacI
Regulation mode:
Biological process: Carbon catabolism
Effector: HPr, phosphocarrier protein; Fructose-1,6-bisphosphate
Regulog: CcpA - Lactobacillaceae
Statistics of regulated genes:
- Genes 57
- Operons 35
Visualization:
Allows to visualize regulon content in the context of metabolic pathways
Built upon 561 sites [see more]
Member of regulog collections
Regulated operons
Locus Tag Name Function

Position: -74
Score: 4
Sequence: TCGTAAACGGTTGCAA
Locus tag: LJ0491
Name: ccpA
Funciton: Carbon catabolism global transcriptional regulator CcpA, LacI family
ccpA
Carbon catabolism global transcriptional regulator CcpA, LacI family

Position: -120
Score: 4
Sequence: ATTAAAGCGCTATTTT
Locus tag: LJ0229
Name: guaA
Funciton: GMP synthase (EC 6.3.5.2)
guaA
GMP synthase (EC 6.3.5.2)

Position: -79
Score: 4.1
Sequence: CAGCAACCGCTTTCAA
Locus tag: LJ1853
Name: spxB
Funciton: Pyruvate oxidase (EC 1.2.3.3)
spxB
Pyruvate oxidase (EC 1.2.3.3)

Position: -53
Score: 5
Sequence: TTGTAAGCGCTTATAA
Locus tag: LJ0211
Name: agl
Funciton: Oligo-1,6-glucosidase (EC 3.2.1.10)
Locus tag: LJ0212
Name: nplT
Funciton: Neopullulanase (EC 3.2.1.135)
agl
Oligo-1,6-glucosidase (EC 3.2.1.10)
nplT
Neopullulanase (EC 3.2.1.135)

Position: -40
Score: 4.1
Sequence: CTGAAAGCGTTTATCA
Locus tag: LJ0570
Name: fruR
Funciton: Fructose utilization transcriptional regulator FruR, DeoR family
Locus tag: LJ0571
Name: fruB
Funciton: 1-phosphofructokinase (EC 2.7.1.56)
Locus tag: LJ0572
Name: fruA
Funciton: Fructose-specific PTS system, IIABC component (EC 2.7.1.69)
fruR
Fructose utilization transcriptional regulator FruR, DeoR family
fruB
1-phosphofructokinase (EC 2.7.1.56)
fruA
Fructose-specific PTS system, IIABC component (EC 2.7.1.69)

Position: -141
Score: 4.7
Sequence: ATGTAAGCGCTATTAT
Locus tag: LJ0623
Name: licT
Funciton: Beta-glucoside bgl operon transcriptional antiterminator, BglG family
licT
Beta-glucoside bgl operon transcriptional antiterminator, BglG family

Position: -173
Score: 4.6
Sequence: AAGAAAGCGCTATCTA
Locus tag: LJ0643
Name: pnuC
Funciton: NrdR-regulated deoxyribonucleotide transporter; Nicotinamide mononucleotide transporter
pnuC
NrdR-regulated deoxyribonucleotide transporter; Nicotinamide mononucleotide transporter

Position: -60
Score: 4.6
Sequence: TTGAAAGTGGTTTCAA
Locus tag: LJ0916
Name: pmi
Funciton: Mannose-6-phosphate isomerase (EC 5.3.1.8)
pmi
Mannose-6-phosphate isomerase (EC 5.3.1.8)

Position: 4
Score: 4.4
Sequence: AAGTATCCGCTTTCAT
Locus tag: LJ0759
Name: treR
Funciton: Trehalose utilization transcriptional regulator TreR, GntR family
Locus tag: LJ0758
Name: treA
Funciton: Trehalose-6-phosphate hydrolase (EC 3.2.1.93)
treR
Trehalose utilization transcriptional regulator TreR, GntR family
treA
Trehalose-6-phosphate hydrolase (EC 3.2.1.93)

Position: -104
Score: 4.4
Sequence: AAGTAAGCTTTTTCAT
Position: -36
Score: 4.5
Sequence: ATGAAAGCGGATACTT
Locus tag: LJ0760
Name: treP
Funciton: Trehalose-specific PTS system, EIIABC component (EC 2.7.1.69)
treP
Trehalose-specific PTS system, EIIABC component (EC 2.7.1.69)

Position: -106
Score: 4.4
Sequence: ATGCAAGCATTTTCAA
Position: -68
Score: 4.1
Sequence: AAGCAAACGTATACAT
Locus tag: LJ0503
Name: manL
Funciton: Mannose-specific PTS system, IIAB component (EC 2.7.1.69)
Locus tag: LJ0504
Name: manM
Funciton: Mannose-specific PTS system, IIC component (EC 2.7.1.69)
Locus tag: LJ0505
Name: manN
Funciton: Mannose-specific PTS system, IID component (EC 2.7.1.69)
Locus tag: LJ0506
Name: manO
Funciton: Predicted regulator of the mannose operon, ManO
manL
Mannose-specific PTS system, IIAB component (EC 2.7.1.69)
manM
Mannose-specific PTS system, IIC component (EC 2.7.1.69)
manN
Mannose-specific PTS system, IID component (EC 2.7.1.69)
manO
Predicted regulator of the mannose operon, ManO

Position: -132
Score: 4.8
Sequence: ATGAAACCGTTTGCAA
Position: -35
Score: 4.3
Sequence: TCGAAAACGCTTACTT
Locus tag: LJ0182
Name: bglA
Funciton: 6-phospho-beta-glucosidase (EC 3.2.1.86)
bglA
6-phospho-beta-glucosidase (EC 3.2.1.86)

Position: -200
Score: 4.6
Sequence: TTGTATTCGCTTTCAA
Position: -166
Score: 4.2
Sequence: ATGTATACGCTTTATA
Locus tag: LJ0259
Name: rafR
Funciton: Raffinose utilization transcriptional regulator RafR, AraC family
rafR
Raffinose utilization transcriptional regulator RafR, AraC family

Position: -82
Score: 4.2
Sequence: CAGTAAACGATTACAT
Locus tag: LJ1656
Name: fmpA
Funciton: Predicted mannose specific PTS system, IIA component
Locus tag: LJ1655
Name: fmpB
Funciton: Predicted mannose specific PTS system, IIB component
Locus tag: LJ1654
Name: fmpC
Funciton: Predicted mannose specific PTS system, IIC component
Locus tag: LJ1653
Name: fmpD
Funciton: Predicted mannose specific PTS system,
Locus tag: LJ1652
Name: fmpE
Funciton: Predicted mannose specific PTS system, putative EII component
fmpA
Predicted mannose specific PTS system, IIA component
fmpB
Predicted mannose specific PTS system, IIB component
fmpC
Predicted mannose specific PTS system, IIC component
fmpD
Predicted mannose specific PTS system,
fmpE
Predicted mannose specific PTS system, putative EII component

Position: -70
Score: 4.5
Sequence: TGTTAAGCGCTTTCAA
Locus tag: LJ0213
Name: mapA
Funciton: Maltose phosphorylase (EC 2.4.1.8) / Trehalose phosphorylase (EC 2.4.1.64)
Locus tag: LJ0214
Name: pgmB
Funciton: Beta-phosphoglucomutase (EC 5.4.2.6)
mapA
Maltose phosphorylase (EC 2.4.1.8) / Trehalose phosphorylase (EC 2.4.1.64)
pgmB
Beta-phosphoglucomutase (EC 5.4.2.6)

Position: -38
Score: 5
Sequence: TTGAAACCGCTTTCTA
Locus tag: LJ0149
Name: pck
Funciton: Phosphoenolpyruvate carboxykinase (EC 4.1.1.49)
pck
Phosphoenolpyruvate carboxykinase (EC 4.1.1.49)

Position: -126
Score: 4.6
Sequence: AAGAAAGCGATATCAT
Locus tag: LJ0542
Name: licT
Funciton: Beta-glucoside bgl operon transcriptional antiterminator, BglG family
Locus tag: LJ0543
Name: bglP
Funciton: Beta-glucoside-specific PTS system, IIBCA component (EC 2.7.1.69)
Locus tag: LJ0544
Name: bglH
Funciton: 6-phospho-beta-glucosidase (EC 3.2.1.86)
licT
Beta-glucoside bgl operon transcriptional antiterminator, BglG family
bglP
Beta-glucoside-specific PTS system, IIBCA component (EC 2.7.1.69)
bglH
6-phospho-beta-glucosidase (EC 3.2.1.86)

Position: -127
Score: 5.2
Sequence: TTGAAAACGCTTTCTT
Locus tag: LJ0635
Name: simA
Funciton: Maltose-6'-phosphate glucosidase (EC 3.2.1.122)
simA
Maltose-6'-phosphate glucosidase (EC 3.2.1.122)

Position: -132
Score: 4.5
Sequence: TTGAAAGCGAAAACAT
Locus tag: LJ1079
Name: pfk
Funciton: 6-phosphofructokinase (EC 2.7.1.11)
Locus tag: LJ1080
Name: pyk
Funciton: Pyruvate kinase (EC 2.7.1.40)
pfk
6-phosphofructokinase (EC 2.7.1.11)
pyk
Pyruvate kinase (EC 2.7.1.40)

Position: -143
Score: 4.6
Sequence: TTGCAATCGTTTACAT
Locus tag: LJ1262
Name: glcT
Funciton: Beta-glucoside bgl operon antiterminator, BglG family
Locus tag: LJ1261
Name: glclP
Funciton: Beta-glucosides PTS, EIIBCA (EC 2.7.1.69)
glcT
Beta-glucoside bgl operon antiterminator, BglG family
glclP
Beta-glucosides PTS, EIIBCA (EC 2.7.1.69)

Position: -28
Score: 4.7
Sequence: ATGTAAGCGATTGCAA
Locus tag: LJ0194
Name: bglB
Funciton: Beta-glucosidase (EC 3.2.1.21); 6-phospho-beta-glucosidase (EC 3.2.1.86)
Locus tag: LJ0193
Name: LBA0884
Funciton: PTS system, IIC component
bglB
Beta-glucosidase (EC 3.2.1.21); 6-phospho-beta-glucosidase (EC 3.2.1.86)
LBA0884
PTS system, IIC component

Position: -162
Score: 4.5
Sequence: ATGTAACCGATAACAT
Locus tag: LJ1766
Name: adhE
Funciton: Alcohol dehydrogenase (EC 1.1.1.1); Acetaldehyde dehydrogenase (EC 1.2.1.10)
adhE
Alcohol dehydrogenase (EC 1.1.1.1); Acetaldehyde dehydrogenase (EC 1.2.1.10)

Position: -44
Score: 4.6
Sequence: AAGAAAGCGCTTTATA
Locus tag: LJ0671
Name: gabD
Funciton: Succinate-semialdehyde dehydrogenase [NAD] (EC 1.2.1.24); Succinate-semialdehyde dehydrogenase [NADP+] (EC 1.2.1.16)
gabD
Succinate-semialdehyde dehydrogenase [NAD] (EC 1.2.1.24); Succinate-semialdehyde dehydrogenase [NADP+] (EC 1.2.1.16)

Position: -85
Score: 4.2
Sequence: TTGCAACCGTTTACGA
Locus tag: LJ0490
Name: pepQ
Funciton: Xaa-Pro dipeptidase (EC 3.4.13.9)
pepQ
Xaa-Pro dipeptidase (EC 3.4.13.9)

Position: -109
Score: 4.6
Sequence: ATGTAAACATTTACAT
Locus tag: LJ0816
Name: ptsH
Funciton: Phosphotransferase system, HPr-related protein
Locus tag: LJ0817
Name: ptsI
Funciton: Phosphoenolpyruvate-protein kinase, PTS system component (EC 2.7.3.9)
ptsH
Phosphotransferase system, HPr-related protein
ptsI
Phosphoenolpyruvate-protein kinase, PTS system component (EC 2.7.3.9)

Position: -214
Score: 4.7
Sequence: GTGTAAGCGTTTTAAA
Position: -184
Score: 4.3
Sequence: ATGATAGCGTATTCTA
Position: -37
Score: 4.6
Sequence: AAGAATGCGTTTACAT
Locus tag: LJ0518
Name: scrB
Funciton: Sucrose-6-phosphate hydrolase (EC 3.2.1.26)
Locus tag: LJ0517
Name: scrR
Funciton: Sucrose operon repressor ScrR, LacI family
scrB
Sucrose-6-phosphate hydrolase (EC 3.2.1.26)
scrR
Sucrose operon repressor ScrR, LacI family

Position: -68
Score: 4.4
Sequence: ATGAAAGCGCTATACT
Locus tag: LJ0485
Name: ackB
Funciton: Acetate kinase (EC 2.7.2.1)
ackB
Acetate kinase (EC 2.7.2.1)

Position: -214
Score: 4.6
Sequence: ATGTAAACGCATTCTT
Position: -37
Score: 4.4
Sequence: TTTAAAACGCTTACAC
Locus tag: LJ0519
Name: scrA
Funciton: Sucrose-specific PTS system, IIABC component (EC 2.7.1.69)
scrA
Sucrose-specific PTS system, IIABC component (EC 2.7.1.69)

Position: -35
Score: 4.6
Sequence: ATGTAAGCGCTAATAA
Locus tag: LJ1256
Name: ydgI
Funciton: Putative NAD(P)H nitroreductase
ydgI
Putative NAD(P)H nitroreductase

Position: -45
Score: 4.4
Sequence: ATAAAAGCGTCTTCAA
Locus tag: LJ0855
Name: lacL
Funciton: Beta-galactosidase large subunit (EC 3.2.1.23)
Locus tag: LJ0854
Name: lacM
Funciton: Beta-galactosidase small subunit (EC 3.2.1.23)
lacL
Beta-galactosidase large subunit (EC 3.2.1.23)
lacM
Beta-galactosidase small subunit (EC 3.2.1.23)

Position: -35
Score: 4.8
Sequence: TTGAAAGCGAATACAA
Locus tag: LJ0569
Name: agl3
Funciton: Alpha-glucosidase (EC 3.2.1.20)
agl3
Alpha-glucosidase (EC 3.2.1.20)

Position: -36
Score: 5.1
Sequence: ATGAAAACGATTACAA
Locus tag: LJ0859
Name: galK
Funciton: Galactokinase (EC 2.7.1.6)
Locus tag: LJ0860
Name: galT
Funciton: Galactose-1-phosphate uridylyltransferase (EC 2.7.7.10)
Locus tag: LJ0861
Name: galM
Funciton: Aldose 1-epimerase (EC 5.1.3.3)
galK
Galactokinase (EC 2.7.1.6)
galT
Galactose-1-phosphate uridylyltransferase (EC 2.7.7.10)
galM
Aldose 1-epimerase (EC 5.1.3.3)

Position: -70
Score: 4.2
Sequence: TATAAAGCGTATACAT
Position: -36
Score: 4.8
Sequence: TTGAAAGCGAATACAA
Locus tag: LJ0260
Name: lacS
Funciton: Lactose and galactose permease
lacS
Lactose and galactose permease

Position: -121
Score: 4.3
Sequence: ATAAAAGCGTTTAATA
Locus tag: LJ0862
Name: null
Funciton: D-Ribose 1,5-phosphomutase (EC 5.4.2.7)
D-Ribose 1,5-phosphomutase (EC 5.4.2.7)

Position: -84
Score: 4.2
Sequence: ATGTTATCGCTTACAG
Locus tag: LJ0171
Name: lacX
Funciton: Aldose 1-epimerase
lacX
Aldose 1-epimerase
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