Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 4.0 --

Regulon of CcpA in Lactobacillus casei ATCC 334

Properties
Regulator type: Transcription factor
TF locus tag: LSEI_0809
Regulator family: LacI
Regulation mode:
Biological process: Carbon catabolism
Effector: HPr, phosphocarrier protein; Fructose-1,6-bisphosphate
Regulog: CcpA - Lactobacillaceae
Statistics of regulated genes:
- Genes 69
- Operons 31
Visualization:
Allows to visualize regulon content in the context of metabolic pathways
Built upon 561 sites [see more]
Member of regulog collections
Regulated operons
Locus Tag Name Function

Position: -94
Score: 4
Sequence: AGTAAAACGCTTGCAT
Locus tag: LSEI_0809
Name: ccpA
Funciton: Carbon catabolism global transcriptional regulator CcpA, LacI family
ccpA
Carbon catabolism global transcriptional regulator CcpA, LacI family

Position: -149
Score: 4
Sequence: GTTTAAGCGTTTTATA
Position: -92
Score: 4.4
Sequence: ATGAAAGGGCTTGCAT
Locus tag: LSEI_1784
Name: spxB
Funciton: Pyruvate oxidase (EC 1.2.3.3)
spxB
Pyruvate oxidase (EC 1.2.3.3)

Position: -230
Score: 4.1
Sequence: TTGTAATCGCTGTTAA
Position: -208
Score: 4.4
Sequence: CAGTAAGCGGTTACAA
Locus tag: LSEI_2040
Name: glgB
Funciton: 1,4-alpha-glucan (glycogen) branching enzyme, GH-13-type (EC 2.4.1.18)
Locus tag: LSEI_2039
Name: glgC
Funciton: Glucose-1-phosphate adenylyltransferase (EC 2.7.7.27)
Locus tag: LSEI_2038
Name: glgD
Funciton: Glucose-1-phosphate adenylyltransferase (EC 2.7.7.27)
Locus tag: LSEI_2037
Name: glgA
Funciton: Glycogen synthase, ADP-glucose transglucosylase (EC 2.4.1.21)
Locus tag: LSEI_2036
Name: glgP
Funciton: Glycogen phosphorylase (EC 2.4.1.1)
Locus tag: LSEI_2035
Name: amy1
Funciton: Neopullulanase (EC 3.2.1.135)
glgB
1,4-alpha-glucan (glycogen) branching enzyme, GH-13-type (EC 2.4.1.18)
glgC
Glucose-1-phosphate adenylyltransferase (EC 2.7.7.27)
glgD
Glucose-1-phosphate adenylyltransferase (EC 2.7.7.27)
glgA
Glycogen synthase, ADP-glucose transglucosylase (EC 2.4.1.21)
glgP
Glycogen phosphorylase (EC 2.4.1.1)
amy1
Neopullulanase (EC 3.2.1.135)

Position: -51
Score: 4.7
Sequence: CTGGAAACGCTTTCAT
Locus tag: LSEI_0662
Name: glpK
Funciton: Glycerol kinase (EC 2.7.1.30)
Locus tag: LSEI_0661
Name: glpD
Funciton: Alpha-glycerophosphate oxidase (EC 1.1.3.21)
Locus tag: LSEI_0660
Name: glpF
Funciton: Glycerol uptake facilitator protein
glpK
Glycerol kinase (EC 2.7.1.30)
glpD
Alpha-glycerophosphate oxidase (EC 1.1.3.21)
glpF
Glycerol uptake facilitator protein

Position: -88
Score: 4.5
Sequence: TTGACAGCGCTTCCAA
Locus tag: LSEI_0306
Name: rbsR
Funciton: Ribose operon transcriptional regulator, LacI family
Locus tag: LSEI_0307
Name: rbsD
Funciton: Ribose ABC transport system, high affinity permease RbsD (TC 3.A.1.2.1)
Locus tag: LSEI_0308
Name: rbsA
Funciton: Ribose ABC transport system, ATP-binding protein RbsA (TC 3.A.1.2.1)
Locus tag: LSEI_0309
Name: rbsC
Funciton: Ribose ABC transport system, permease protein RbsC (TC 3.A.1.2.1)
Locus tag: LSEI_0310
Name: null
Funciton: Ribose ABC transport system, periplasmic ribose-binding protein RbsB (TC 3.A.1.2.1)
rbsR
Ribose operon transcriptional regulator, LacI family
rbsD
Ribose ABC transport system, high affinity permease RbsD (TC 3.A.1.2.1)
rbsA
Ribose ABC transport system, ATP-binding protein RbsA (TC 3.A.1.2.1)
rbsC
Ribose ABC transport system, permease protein RbsC (TC 3.A.1.2.1)
Ribose ABC transport system, periplasmic ribose-binding protein RbsB (TC 3.A.1.2.1)

Position: -108
Score: 4
Sequence: ATGAAAACGATGAAAA
Locus tag: LSEI_0748
Name: ndk
Funciton: Nucleoside diphosphate kinase (EC 2.7.4.6)
ndk
Nucleoside diphosphate kinase (EC 2.7.4.6)

Position: -80
Score: 4.4
Sequence: TTGATAACGGTAACAA
Locus tag: LSEI_0980
Name: nplT
Funciton: Neopullulanase (EC 3.2.1.135)
nplT
Neopullulanase (EC 3.2.1.135)

Position: -89
Score: 4.6
Sequence: TTGAAAACGCTTGTAA
Position: -39
Score: 4.3
Sequence: CAGAAAACGATTACAT
Locus tag: LSEI_2817
Name: pts20B
Funciton: PTS system, cellobiose-specific IIB component (EC 2.7.1.69)
Locus tag: LSEI_2818
Name: pts20A
Funciton: PTS system, cellobiose-specific IIA component (EC 2.7.1.69)
pts20B
PTS system, cellobiose-specific IIB component (EC 2.7.1.69)
pts20A
PTS system, cellobiose-specific IIA component (EC 2.7.1.69)

Position: -65
Score: 4.5
Sequence: TTGTCAGCGATTACAT
Locus tag: LSEI_2888
Name: mtlA
Funciton: Mannitol-specific PTS system, IIBC component (EC 2.7.1.69)
Locus tag: LSEI_2887
Name: mtlR
Funciton: Mannitol operon antiterminator, BglG family
Locus tag: LSEI_2886
Name: mtlF
Funciton: Mannitol-specific PTS system, mannitol-specific IIA component (EC 2.7.1.69)
Locus tag: LSEI_2885
Name: mtlD
Funciton: Mannitol-1-phosphate 5-dehydrogenase (EC 1.1.1.17)
mtlA
Mannitol-specific PTS system, IIBC component (EC 2.7.1.69)
mtlR
Mannitol operon antiterminator, BglG family
mtlF
Mannitol-specific PTS system, mannitol-specific IIA component (EC 2.7.1.69)
mtlD
Mannitol-1-phosphate 5-dehydrogenase (EC 1.1.1.17)

Position: -90
Score: 4.8
Sequence: TTGAATGCGGTTACAA
Locus tag: LSEI_2769
Name: LBA0143
Funciton: Maltodextrin glucosidase (EC 3.2.1.20); Alpha-glucosidase, family 31 of glycosyl hydrolase
LBA0143
Maltodextrin glucosidase (EC 3.2.1.20); Alpha-glucosidase, family 31 of glycosyl hydrolase

Position: -101
Score: 4.1
Sequence: TCGAAATCGCTTTCTT
Locus tag: LSEI_1473
Name: lplA1
Funciton: Lipoate-protein ligase A
lplA1
Lipoate-protein ligase A

Position: -111
Score: 4.2
Sequence: AATAAAACGCTTGCAA
Position: -68
Score: 4.1
Sequence: TTGTAAAGATTTTCAT
Locus tag: LSEI_1305
Name: pdhA
Funciton: Dihydrolipoamide dehydrogenase complex (EC 1.8.1.4), E1 component alpha-subunit
Locus tag: LSEI_1306
Name: pdhB
Funciton: Dihydrolipoamide dehydrogenase complex (EC 1.8.1.4), E1 component beta-subunit
Locus tag: LSEI_1307
Name: pdhC
Funciton: Dihydrolipoamide dehydrogenase complex (EC 1.8.1.4), E2 component
Locus tag: LSEI_1308
Name: pdhD
Funciton: Dihydrolipoamide dehydrogenase complex (EC 1.8.1.4), E3 component
pdhA
Dihydrolipoamide dehydrogenase complex (EC 1.8.1.4), E1 component alpha-subunit
pdhB
Dihydrolipoamide dehydrogenase complex (EC 1.8.1.4), E1 component beta-subunit
pdhC
Dihydrolipoamide dehydrogenase complex (EC 1.8.1.4), E2 component
pdhD
Dihydrolipoamide dehydrogenase complex (EC 1.8.1.4), E3 component

Position: -90
Score: 4.2
Sequence: TTAAAAGCGTTTAAAC
Position: -27
Score: 4.3
Sequence: GTGAAAGCGATTTCTG
Locus tag: LSEI_0629
Name: treR
Funciton: Trehalose utilization transcriptional regulator TreR, GntR family
Locus tag: LSEI_0630
Name: treA
Funciton: Trehalose-6-phosphate hydrolase (EC 3.2.1.93)
Locus tag: LSEI_0631
Name: treP
Funciton: Trehalose-specific PTS system, EIIABC component (EC 2.7.1.69)
treR
Trehalose utilization transcriptional regulator TreR, GntR family
treA
Trehalose-6-phosphate hydrolase (EC 3.2.1.93)
treP
Trehalose-specific PTS system, EIIABC component (EC 2.7.1.69)

Position: -200
Score: 4.5
Sequence: TTGTAAGCGTTAACCT
Locus tag: LSEI_0559
Name: fmpA
Funciton: Predicted mannose specific PTS system, IIA component
Locus tag: LSEI_0560
Name: fmpB
Funciton: Predicted mannose specific PTS system, IIB component
Locus tag: LSEI_0561
Name: fmpC
Funciton: Predicted mannose specific PTS system, IIC component
Locus tag: LSEI_0562
Name: fmpD
Funciton: Predicted mannose specific PTS system,
Locus tag: LSEI_0563
Name: fmpE
Funciton: Predicted mannose specific PTS system, putative EII component
fmpA
Predicted mannose specific PTS system, IIA component
fmpB
Predicted mannose specific PTS system, IIB component
fmpC
Predicted mannose specific PTS system, IIC component
fmpD
Predicted mannose specific PTS system,
fmpE
Predicted mannose specific PTS system, putative EII component

Position: -115
Score: 4.5
Sequence: GAGAAAGCGCTTATAA
Locus tag: LSEI_2296
Name: cad
Funciton: Predicted pheromone precursor lipoprotein, related to Cad
cad
Predicted pheromone precursor lipoprotein, related to Cad

Position: -105
Score: 4.9
Sequence: TTGAAACCGCTTGCAT
Locus tag: LSEI_0369
Name: simA
Funciton: Maltose-6'-phosphate glucosidase (EC 3.2.1.122)
simA
Maltose-6'-phosphate glucosidase (EC 3.2.1.122)

Position: -79
Score: 4.6
Sequence: TTATAAACGCTTTCAG
Position: -30
Score: 4.5
Sequence: TTGGAATCGTTTTAAT
Locus tag: LSEI_2070
Name: lulA
Funciton: Lactate utilization protein A
Locus tag: LSEI_2069
Name: lulC
Funciton: Lactate utilization protein C
Locus tag: LSEI_2068
Name: lulB
Funciton: Lactate utilization protein B
lulA
Lactate utilization protein A
lulC
Lactate utilization protein C
lulB
Lactate utilization protein B

Position: -18
Score: 4.1
Sequence: AAGGGAGCGTTTTCAA
Locus tag: LSEI_2278
Name: gabD
Funciton: Succinate-semialdehyde dehydrogenase [NAD] (EC 1.2.1.24); Succinate-semialdehyde dehydrogenase [NADP+] (EC 1.2.1.16)
gabD
Succinate-semialdehyde dehydrogenase [NAD] (EC 1.2.1.24); Succinate-semialdehyde dehydrogenase [NADP+] (EC 1.2.1.16)

Position: -229
Score: 4.2
Sequence: ATGCAAGCGTTTTACT
Locus tag: LSEI_0808
Name: pepQ
Funciton: Xaa-Pro dipeptidase (EC 3.4.13.9)
pepQ
Xaa-Pro dipeptidase (EC 3.4.13.9)

Position: -127
Score: 4.5
Sequence: ATGATAGCGGTAACAT
Locus tag: LSEI_0982
Name: mapA
Funciton: Maltose phosphorylase (EC 2.4.1.8) / Trehalose phosphorylase (EC 2.4.1.64)
Locus tag: LSEI_0983
Name: pgmB
Funciton: Beta-phosphoglucomutase (EC 5.4.2.6)
mapA
Maltose phosphorylase (EC 2.4.1.8) / Trehalose phosphorylase (EC 2.4.1.64)
pgmB
Beta-phosphoglucomutase (EC 5.4.2.6)

Position: -81
Score: 4.3
Sequence: CTGAAACCGTATACAA
Position: -14
Score: 4.1
Sequence: AAGGAAGCTGTTTCAT
Locus tag: LSEI_2045
Name: fbp
Funciton: Fructose-1,6-bisphosphatase, Bacillus type (EC 3.1.3.11)
fbp
Fructose-1,6-bisphosphatase, Bacillus type (EC 3.1.3.11)

Position: -193
Score: 4
Sequence: CTGGAAACGCTTACGT
Locus tag: LSEI_2549
Name: ldh
Funciton: L-lactate dehydrogenase (EC 1.1.1.27)
ldh
L-lactate dehydrogenase (EC 1.1.1.27)

Position: -43
Score: 4.9
Sequence: TTGTAAGCGATTTCTT
Locus tag: LSEI_0229
Name: gntP
Funciton: H+/gluconate symporter related permease
gntP
H+/gluconate symporter related permease

Position: -98
Score: 4.7
Sequence: TTGAAAGCGCTATCGT
Locus tag: LSEI_0715
Name: yxjF
Funciton: Predicted short-chain alcohol dehydrogenase
Locus tag: LSEI_0716
Name: adc
Funciton: Probable acetoacetate decarboxylase
Locus tag: LSEI_0717
Name: ydgI
Funciton: Putative NAD(P)H nitroreductase
yxjF
Predicted short-chain alcohol dehydrogenase
adc
Probable acetoacetate decarboxylase
ydgI
Putative NAD(P)H nitroreductase

Position: -36
Score: 4.5
Sequence: TTGAATGCGTTTTCGT
Locus tag: LSEI_2598
Name: lacX
Funciton: Aldose 1-epimerase
lacX
Aldose 1-epimerase

Position: -102
Score: 3.9
Sequence: TTGAGCGCGTTTTCAA
Locus tag: LSEI_0949
Name: null
Funciton: Phosphoglucosamine mutase (EC 5.4.2.10) / Phosphomannomutase (EC 5.4.2.8)
Phosphoglucosamine mutase (EC 5.4.2.10) / Phosphomannomutase (EC 5.4.2.8)

Position: -69
Score: 4.2
Sequence: TTGTAAGCGTATCCAG
Locus tag: LSEI_2739
Name: ulaG
Funciton: Probable L-ascorbate-6-phosphate lactonase UlaG (EC 3.1.1.-) (L-ascorbate utilization protein G)
Locus tag: LSEI_2738
Name: ulaC
Funciton: Ascorbate-specific PTS system, EIIA component (EC 2.7.1.-)
Locus tag: LSEI_2737
Name: ulaA
Funciton: Ascorbate-specific PTS system, EIIC component
Locus tag: LSEI_2736
Name: ulaB
Funciton: Ascorbate-specific PTS system, EIIB component (EC 2.7.1.69)
Locus tag: LSEI_2735
Name: ulaD
Funciton: 3-keto-L-gulonate 6-phosphate decarboxylase (EC 4.1.1.85)
ulaG
Probable L-ascorbate-6-phosphate lactonase UlaG (EC 3.1.1.-) (L-ascorbate utilization protein G)
ulaC
Ascorbate-specific PTS system, EIIA component (EC 2.7.1.-)
ulaA
Ascorbate-specific PTS system, EIIC component
ulaB
Ascorbate-specific PTS system, EIIB component (EC 2.7.1.69)
ulaD
3-keto-L-gulonate 6-phosphate decarboxylase (EC 4.1.1.85)

Position: -65
Score: 4.7
Sequence: ATAAAAACGGTTACAA
Locus tag: LSEI_0664
Name: galK
Funciton: Galactokinase (EC 2.7.1.6)
Locus tag: LSEI_0665
Name: galE
Funciton: UDP-glucose 4-epimerase (EC 5.1.3.2)
Locus tag: LSEI_0666
Name: galT
Funciton: Galactose-1-phosphate uridylyltransferase (EC 2.7.7.10)
Locus tag: LSEI_0667
Name: galR
Funciton: Galactose utilization transcriptional regulator GalR, LacI family
Locus tag: LSEI_0668
Name: galM
Funciton: Aldose 1-epimerase (EC 5.1.3.3)
galK
Galactokinase (EC 2.7.1.6)
galE
UDP-glucose 4-epimerase (EC 5.1.3.2)
galT
Galactose-1-phosphate uridylyltransferase (EC 2.7.7.10)
galR
Galactose utilization transcriptional regulator GalR, LacI family
galM
Aldose 1-epimerase (EC 5.1.3.3)

Position: -140
Score: 4.5
Sequence: ATGAAATCGGATACAT
Locus tag: LSEI_0634
Name: null
Funciton: L-lactate dehydrogenase (EC 1.1.1.27)
L-lactate dehydrogenase (EC 1.1.1.27)

Position: -62
Score: 4
Sequence: ATGAAACCACTCTCAT
Locus tag: LSEI_1126
Name: pgi
Funciton: Glucose-6-phosphate isomerase (EC 5.3.1.9)
pgi
Glucose-6-phosphate isomerase (EC 5.3.1.9)

Position: -304
Score: 4.1
Sequence: ATGTAACGGCTTATAT
Locus tag: LSEI_2729
Name: sorD
Funciton: Sorbitol-6-phosphate 2-dehydrogenase (EC 1.1.1.140)
Locus tag: LSEI_2728
Name: srlM
Funciton: Sorbitol operon transcription regulator
sorD
Sorbitol-6-phosphate 2-dehydrogenase (EC 1.1.1.140)
srlM
Sorbitol operon transcription regulator
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