Regulon of CcpA in Lactobacillus acidophilus NCFM
| Regulator type: | Transcription factor |
| TF locus tag: | LBA0431 |
| Regulator family: | LacI |
| Regulation mode: | |
| Biological process: | Carbon catabolism |
| Effector: | HPr, phosphocarrier protein; Fructose-1,6-bisphosphate |
| Regulog: | CcpA - Lactobacillaceae |
| Statistics of regulated genes: | |
| - Genes | 70 |
| - Operons | 37 |
| Visualization: | |
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Allows to visualize regulon content in the context of metabolic pathways |
Member of regulog collections
- By taxonomy - Lactobacillaceae
- By trascription factor - CcpA
- By TF family - LacI
- By effector - HPr, phosphocarrier protein
- By effector - Fructose-1,6-bisphosphate
- By pathway - Carbon catabolism
| Locus Tag | Name | Function | |
|---|---|---|---|
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Position: -75
Score: 4.4 Sequence: CTGTAAACGTTTGCAA
Locus tag: LBA0431
Name: ccpA Funciton: Carbon catabolism global transcriptional regulator CcpA, LacI family |
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ccpA
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Carbon catabolism global transcriptional regulator CcpA, LacI family
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Position: -110
Score: 4.4 Sequence: GAAAAAGCGGTTTCAT
Position: -78
Score: 4 Sequence: AAGATAGCGTTTTGAA
Locus tag: LBA1974
Name: spxB Funciton: Pyruvate oxidase (EC 1.2.3.3) |
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spxB
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Pyruvate oxidase (EC 1.2.3.3)
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Position: -61
Score: 4.1 Sequence: TTGGATGCGTTTTTTT
Locus tag: LBA0587
Name: rbsK Funciton: Ribokinase (EC 2.7.1.15)
Locus tag: LBA0588
Name: rpiA Funciton: Ribose 5-phosphate isomerase A (EC 5.3.1.6) |
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rbsK
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Ribokinase (EC 2.7.1.15)
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rpiA
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Ribose 5-phosphate isomerase A (EC 5.3.1.6)
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Position: -101
Score: 4.7 Sequence: TTGAAAGCGATTACAC
Locus tag: LBA1485
Name: rbsK Funciton: Ribokinase (EC 2.7.1.15)
Locus tag: LBA1484
Name: rbsD Funciton: Ribose ABC transport system, high affinity permease RbsD (TC 3.A.1.2.1)
Locus tag: LBA1483
Name: rbsA Funciton: Ribose ABC transport system, ATP-binding protein RbsA (TC 3.A.1.2.1)
Locus tag: LBA1482
Name: rbsC Funciton: Ribose ABC transport system, permease protein RbsC (TC 3.A.1.2.1)
Locus tag: LBA1481
Name: rbsB Funciton: Ribose ABC transport system, periplasmic ribose-binding protein RbsB (TC 3.A.1.2.1) |
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rbsK
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Ribokinase (EC 2.7.1.15)
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rbsD
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Ribose ABC transport system, high affinity permease RbsD (TC 3.A.1.2.1)
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rbsA
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Ribose ABC transport system, ATP-binding protein RbsA (TC 3.A.1.2.1)
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rbsC
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Ribose ABC transport system, permease protein RbsC (TC 3.A.1.2.1)
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rbsB
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Ribose ABC transport system, periplasmic ribose-binding protein RbsB (TC 3.A.1.2.1)
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Position: -53
Score: 5.1 Sequence: ATGAAAGCGCTTAAAA
Locus tag: LBA1442
Name: msmE Funciton: Multiple sugar ABC transporter, substrate-binding protein
Locus tag: LBA1441
Name: msmF Funciton: Multiple sugar ABC transporter, permease protein 2
Locus tag: LBA1440
Name: msmG Funciton: Multiple sugar ABC transporter, permease protein 1 |
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msmE
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Multiple sugar ABC transporter, substrate-binding protein
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msmF
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Multiple sugar ABC transporter, permease protein 2
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msmG
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Multiple sugar ABC transporter, permease protein 1
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Position: -49
Score: 5 Sequence: TTGAAAACGGTTTCTT
Locus tag: LBA1872
Name: agl Funciton: Oligo-1,6-glucosidase (EC 3.2.1.10)
Locus tag: LBA1871
Name: nplT Funciton: Neopullulanase (EC 3.2.1.135) |
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agl
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Oligo-1,6-glucosidase (EC 3.2.1.10)
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nplT
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Neopullulanase (EC 3.2.1.135)
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Position: -205
Score: 3.8 Sequence: ATGAAACCAGTATTAT
Locus tag: LBA0271
Name: ldh Funciton: L-lactate dehydrogenase (EC 1.1.1.27) |
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ldh
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L-lactate dehydrogenase (EC 1.1.1.27)
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Position: -196
Score: 4.3 Sequence: TTTAAAACATTTTCAT
Position: -163
Score: 4.8 Sequence: TTGACACCGCTTTCAA
Locus tag: LBA0724
Name: licT Funciton: Beta-glucoside bgl operon transcriptional antiterminator, BglG family |
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licT
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Beta-glucoside bgl operon transcriptional antiterminator, BglG family
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Position: -190
Score: 4.7 Sequence: ATAAAAGCGTTTTAAA
Locus tag: LBA1653
Name: pnuC Funciton: NrdR-regulated deoxyribonucleotide transporter; Nicotinamide mononucleotide transporter |
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pnuC
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NrdR-regulated deoxyribonucleotide transporter; Nicotinamide mononucleotide transporter
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Position: -42
Score: 4.5 Sequence: ATAAAAGCGGATTCAT
Locus tag: LBA0452
Name: manL Funciton: Mannose-specific PTS system, IIAB component (EC 2.7.1.69)
Locus tag: LBA0455
Name: manM Funciton: Mannose-specific PTS system, IIC component (EC 2.7.1.69)
Locus tag: LBA0456
Name: manN Funciton: Mannose-specific PTS system, IID component (EC 2.7.1.69)
Locus tag: LBA0457
Name: manO Funciton: Predicted regulator of the mannose operon, ManO |
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manL
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Mannose-specific PTS system, IIAB component (EC 2.7.1.69)
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manM
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Mannose-specific PTS system, IIC component (EC 2.7.1.69)
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manN
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Mannose-specific PTS system, IID component (EC 2.7.1.69)
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manO
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Predicted regulator of the mannose operon, ManO
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Position: -58
Score: 4.3 Sequence: AAGAAAAGGGTTTCAT
Locus tag: LBA0745
Name: pmi Funciton: Mannose-6-phosphate isomerase (EC 5.3.1.8) |
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pmi
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Mannose-6-phosphate isomerase (EC 5.3.1.8)
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Position: -169
Score: 4.7 Sequence: TATAAAGCGTTTTCAT
Position: -102
Score: 4.5 Sequence: TTGAAAGCGATCACAA
Locus tag: LBA1013
Name: treR Funciton: Trehalose utilization transcriptional regulator TreR, GntR family
Locus tag: LBA1014
Name: treA Funciton: Trehalose-6-phosphate hydrolase (EC 3.2.1.93) |
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treR
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Trehalose utilization transcriptional regulator TreR, GntR family
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treA
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Trehalose-6-phosphate hydrolase (EC 3.2.1.93)
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Position: -96
Score: 4.3 Sequence: TTGTGATCGCTTTCAA
Position: -29
Score: 4.8 Sequence: ATGAAAACGCTTTATA
Locus tag: LBA1012
Name: treP Funciton: Trehalose-specific PTS system, EIIABC component (EC 2.7.1.69) |
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treP
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Trehalose-specific PTS system, EIIABC component (EC 2.7.1.69)
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Position: -37
Score: 4.2 Sequence: GAGAAAGCGAATACAA
Locus tag: LBA1779
Name: fruR Funciton: Fructose utilization transcriptional regulator FruR, DeoR family
Locus tag: LBA1778
Name: fruB Funciton: 1-phosphofructokinase (EC 2.7.1.56)
Locus tag: LBA1777
Name: fruA Funciton: Fructose-specific PTS system, IIABC component (EC 2.7.1.69) |
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fruR
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Fructose utilization transcriptional regulator FruR, DeoR family
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fruB
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1-phosphofructokinase (EC 2.7.1.56)
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fruA
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Fructose-specific PTS system, IIABC component (EC 2.7.1.69)
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Position: -44
Score: 4.9 Sequence: ATGCAAACGTTTTCAA
Locus tag: LBA0874
Name: bglA Funciton: 6-phospho-beta-glucosidase (EC 3.2.1.86) |
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bglA
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6-phospho-beta-glucosidase (EC 3.2.1.86)
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Position: -206
Score: 5 Sequence: TTTTAAGCGCTTTCAT
Locus tag: LBA1443
Name: rafR Funciton: Raffinose utilization transcriptional regulator RafR, AraC family |
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rafR
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Raffinose utilization transcriptional regulator RafR, AraC family
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Position: -131
Score: 5.1 Sequence: ATGAAAGCGTTATCAT
Locus tag: LBA1708
Name: licT Funciton: Beta-glucoside bgl operon transcriptional antiterminator, BglG family
Locus tag: LBA1707
Name: bglP Funciton: Beta-glucoside-specific PTS system, IIBCA component (EC 2.7.1.69)
Locus tag: LBA1706
Name: bglH Funciton: 6-phospho-beta-glucosidase (EC 3.2.1.86) |
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licT
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Beta-glucoside bgl operon transcriptional antiterminator, BglG family
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bglP
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Beta-glucoside-specific PTS system, IIBCA component (EC 2.7.1.69)
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bglH
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6-phospho-beta-glucosidase (EC 3.2.1.86)
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Position: -100
Score: 4.5 Sequence: GTGAAAGCGAATACAT
Locus tag: LBA1689
Name: simA Funciton: Maltose-6'-phosphate glucosidase (EC 3.2.1.122) |
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simA
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Maltose-6'-phosphate glucosidase (EC 3.2.1.122)
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Position: -134
Score: 4.2 Sequence: ATGTAAGTGCTAACAT
Locus tag: LBA0956
Name: pfk Funciton: 6-phosphofructokinase (EC 2.7.1.11)
Locus tag: LBA0957
Name: pyk Funciton: Pyruvate kinase (EC 2.7.1.40) |
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pfk
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6-phosphofructokinase (EC 2.7.1.11)
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pyk
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Pyruvate kinase (EC 2.7.1.40)
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Position: -138
Score: 4.7 Sequence: TTGCAATCGCTTACAT
Locus tag: LBA1479
Name: glcT Funciton: Beta-glucoside bgl operon antiterminator, BglG family
Locus tag: LBA1478
Name: glclP Funciton: Beta-glucosides PTS, EIIBCA (EC 2.7.1.69) |
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glcT
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Beta-glucoside bgl operon antiterminator, BglG family
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glclP
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Beta-glucosides PTS, EIIBCA (EC 2.7.1.69)
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Position: -161
Score: 4.3 Sequence: AAGCAAGCGCTTCCAT
Locus tag: LBA0461
Name: adhE Funciton: Alcohol dehydrogenase (EC 1.1.1.1); Acetaldehyde dehydrogenase (EC 1.2.1.10) |
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adhE
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Alcohol dehydrogenase (EC 1.1.1.1); Acetaldehyde dehydrogenase (EC 1.2.1.10)
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Position: -66
Score: 4.7 Sequence: TTGTAAACGCTTTATA
Locus tag: LBA1632
Name: gabD Funciton: Succinate-semialdehyde dehydrogenase [NAD] (EC 1.2.1.24); Succinate-semialdehyde dehydrogenase [NADP+] (EC 1.2.1.16) |
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gabD
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Succinate-semialdehyde dehydrogenase [NAD] (EC 1.2.1.24); Succinate-semialdehyde dehydrogenase [NADP+] (EC 1.2.1.16)
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Position: -74
Score: 4.4 Sequence: TGTAAACCGCTTTCAA
Position: -48
Score: 4.6 Sequence: ATGAAAGCGTAAACAA
Locus tag: LBA1870
Name: mapA Funciton: Maltose phosphorylase (EC 2.4.1.8) / Trehalose phosphorylase (EC 2.4.1.64)
Locus tag: LBA1869
Name: pgmB Funciton: Beta-phosphoglucomutase (EC 5.4.2.6) |
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mapA
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Maltose phosphorylase (EC 2.4.1.8) / Trehalose phosphorylase (EC 2.4.1.64)
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pgmB
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Beta-phosphoglucomutase (EC 5.4.2.6)
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Position: -85
Score: 4.6 Sequence: TTGCAAACGTTTACAG
Locus tag: LBA0430
Name: pepQ Funciton: Xaa-Pro dipeptidase (EC 3.4.13.9) |
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pepQ
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Xaa-Pro dipeptidase (EC 3.4.13.9)
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Position: -111
Score: 4.4 Sequence: ATGTAAACTGTTACAT
Locus tag: LBA0639
Name: ptsH Funciton: Phosphotransferase system, HPr-related protein
Locus tag: LBA0640
Name: ptsI Funciton: Phosphoenolpyruvate-protein kinase, PTS system component (EC 2.7.3.9) |
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ptsH
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Phosphotransferase system, HPr-related protein
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ptsI
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Phosphoenolpyruvate-protein kinase, PTS system component (EC 2.7.3.9)
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Position: -220
Score: 4.9 Sequence: ATGTAAACGCTTTTAT
Position: -188
Score: 4.5 Sequence: ATGATAACGTATTCAA
Position: -31
Score: 4.6 Sequence: AAGATAACGCTTACAT
Locus tag: LBA0400
Name: scrB Funciton: Sucrose-6-phosphate hydrolase (EC 3.2.1.26)
Locus tag: LBA0399
Name: scrR Funciton: Sucrose operon repressor ScrR, LacI family |
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scrB
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Sucrose-6-phosphate hydrolase (EC 3.2.1.26)
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scrR
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Sucrose operon repressor ScrR, LacI family
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Position: -54
Score: 4.6 Sequence: TTGCAACCGATTTCAT
Locus tag: LBA0225
Name: bglA Funciton: 6-phospho-beta-glucosidase (EC 3.2.1.86) |
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bglA
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6-phospho-beta-glucosidase (EC 3.2.1.86)
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Position: -72
Score: 4.4 Sequence: ATGAAAGCGCTATACT
Locus tag: LBA1873
Name: ackB Funciton: Acetate kinase (EC 2.7.2.1) |
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ackB
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Acetate kinase (EC 2.7.2.1)
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Position: -219
Score: 4.7 Sequence: ATGTAAGCGTTATCTT
Position: -30
Score: 4.9 Sequence: ATAAAAGCGTTTACAT
Locus tag: LBA0401
Name: scrA Funciton: Sucrose-specific PTS system, IIABC component (EC 2.7.1.69) |
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scrA
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Sucrose-specific PTS system, IIABC component (EC 2.7.1.69)
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Position: -47
Score: 5 Sequence: ATAAAAGCGTTTTCAA
Locus tag: LBA1467
Name: lacL Funciton: Beta-galactosidase large subunit (EC 3.2.1.23)
Locus tag: LBA1468
Name: lacM Funciton: Beta-galactosidase small subunit (EC 3.2.1.23) |
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lacL
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Beta-galactosidase large subunit (EC 3.2.1.23)
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lacM
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Beta-galactosidase small subunit (EC 3.2.1.23)
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Position: -40
Score: 4.8 Sequence: TTGAAAGCGAATACAT
Locus tag: LBA1812
Name: agl3 Funciton: Alpha-glucosidase (EC 3.2.1.20) |
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agl3
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Alpha-glucosidase (EC 3.2.1.20)
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Position: -90
Score: 4.3 Sequence: GTGAATGCGCTTATAA
Locus tag: LBA0752
Name: pgi Funciton: Glucose-6-phosphate isomerase (EC 5.3.1.9) |
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pgi
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Glucose-6-phosphate isomerase (EC 5.3.1.9)
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Position: -36
Score: 4.3 Sequence: CTGAAAACGATTACAG
Locus tag: LBA1459
Name: galK Funciton: Galactokinase (EC 2.7.1.6)
Locus tag: LBA1458
Name: galT Funciton: Galactose-1-phosphate uridylyltransferase (EC 2.7.7.10)
Locus tag: LBA1457
Name: galM Funciton: Aldose 1-epimerase (EC 5.1.3.3) |
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galK
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Galactokinase (EC 2.7.1.6)
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galT
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Galactose-1-phosphate uridylyltransferase (EC 2.7.7.10)
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galM
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Aldose 1-epimerase (EC 5.1.3.3)
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Position: -55
Score: 4.3 Sequence: AAGTAAGCGCTTTCCG
Locus tag: LBA0680
Name: glgB Funciton: 1,4-alpha-glucan (glycogen) branching enzyme, GH-13-type (EC 2.4.1.18)
Locus tag: LBA0681
Name: glgC Funciton: Glucose-1-phosphate adenylyltransferase (EC 2.7.7.27)
Locus tag: LBA0682
Name: glgD Funciton: Glucose-1-phosphate adenylyltransferase (EC 2.7.7.27)
Locus tag: LBA0683
Name: glgA Funciton: Glycogen synthase, ADP-glucose transglucosylase (EC 2.4.1.21)
Locus tag: LBA0685
Name: glgP Funciton: Glycogen phosphorylase (EC 2.4.1.1)
Locus tag: LBA0686
Name: amy1 Funciton: Neopullulanase (EC 3.2.1.135) |
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glgB
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1,4-alpha-glucan (glycogen) branching enzyme, GH-13-type (EC 2.4.1.18)
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glgC
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Glucose-1-phosphate adenylyltransferase (EC 2.7.7.27)
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glgD
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Glucose-1-phosphate adenylyltransferase (EC 2.7.7.27)
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glgA
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Glycogen synthase, ADP-glucose transglucosylase (EC 2.4.1.21)
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glgP
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Glycogen phosphorylase (EC 2.4.1.1)
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amy1
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Neopullulanase (EC 3.2.1.135)
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Position: -35
Score: 4.7 Sequence: TTGTAAGCGATTGCAT
Locus tag: LBA1433
Name: dhaK Funciton: Phosphoenolpyruvate-dihydroxyacetone phosphotransferase (EC 2.7.1.121), dihydroxyacetone binding subunit DhaK
Locus tag: LBA1434
Name: dhaL Funciton: Phosphoenolpyruvate-dihydroxyacetone phosphotransferase (EC 2.7.1.121), ADP-binding subunit DhaL
Locus tag: LBA1435
Name: dhaM Funciton: Phosphoenolpyruvate-dihydroxyacetone phosphotransferase (EC 2.7.1.121), subunit DhaM; DHA-specific IIA component
Locus tag: LBA1436
Name: glpF2 Funciton: Glycerol uptake facilitator protein |
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dhaK
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Phosphoenolpyruvate-dihydroxyacetone phosphotransferase (EC 2.7.1.121), dihydroxyacetone binding subunit DhaK
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dhaL
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Phosphoenolpyruvate-dihydroxyacetone phosphotransferase (EC 2.7.1.121), ADP-binding subunit DhaL
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dhaM
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Phosphoenolpyruvate-dihydroxyacetone phosphotransferase (EC 2.7.1.121), subunit DhaM; DHA-specific IIA component
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glpF2
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Glycerol uptake facilitator protein
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Position: -35
Score: 4.8 Sequence: ATGAAAGCGATTACAG
Locus tag: LBA0885
Name: bglB Funciton: Beta-glucosidase (EC 3.2.1.21); 6-phospho-beta-glucosidase (EC 3.2.1.86)
Locus tag: LBA0884
Name: LBA0884 Funciton: PTS system, IIC component |
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bglB
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Beta-glucosidase (EC 3.2.1.21); 6-phospho-beta-glucosidase (EC 3.2.1.86)
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LBA0884
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PTS system, IIC component
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Position: -52
Score: 4.4 Sequence: ATGAAAGAGGTTACAA
Locus tag: LBA1401
Name: hcaD Funciton: NADH peroxidase (EC 1.11.1.1) |
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hcaD
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NADH peroxidase (EC 1.11.1.1)
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Regulated Genes | [ Tab delimited format ] | DOWNLOAD |
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Regulatory Sites | [ FASTA format ] | DOWNLOAD |