Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 4.0 --

Regulon of Cobalamin in Roseiflexus sp. RS-1

Properties
Regulator type: RNA regulatory element
Name: Cobalamin
RFAM: RF00174
Regulation mode:
Biological process: Cobalamin biosynthesis
Effector: Adenosylcobalamin
Regulog: Cobalamin - Chloroflexia
Under regulation:
- Genes 32
- Operons 3
Member of regulog collections
Regulated operons
Locus Tag Name Function

Position: -344
Score: 63.8
Sequence: TAAACCTTTCAAACG...
Locus tag: RoseRS_3103
Name: null
Funciton: hypothetical protein
Locus tag: RoseRS_3102
Name: RoseRS_3102
Funciton: Core component MTH452 of predicted ECF transporter
Locus tag: RoseRS_3101
Name: RoseRS_3101
Funciton: Transmembrane component of energizing module of ECF transporters
Locus tag: RoseRS_3100
Name: RoseRS_3100
Funciton: Duplicated ATPase component of energizing module of ECF transporters / ATPase component of general energizing module of ECF transporters
Locus tag: RoseRS_3099
Name: cobN
Funciton: Cobaltochelatase subunit CobN
Locus tag: RoseRS_3098
Name: null
Funciton: hypothetical protein
hypothetical protein
RoseRS_3102
Core component MTH452 of predicted ECF transporter
RoseRS_3101
Transmembrane component of energizing module of ECF transporters
RoseRS_3100
Duplicated ATPase component of energizing module of ECF transporters / ATPase component of general energizing module of ECF transporters
cobN
Cobaltochelatase subunit CobN
hypothetical protein

Position: -361
Score: 62
Sequence: AATGCAACGACCGTC...
Locus tag: RoseRS_0557
Name: btuR
Funciton: Cob(I)alamin adenosyltransferase (EC 2.5.1.17)
Locus tag: RoseRS_0558
Name: cobN
Funciton: CobN component of cobalt chelatase involved in B12 biosynthesis
Locus tag: RoseRS_0559
Name: cobT
Funciton: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21)
Locus tag: RoseRS_0560
Name: cbiM
Funciton: Substrate-specific component CbiM of cobalt ECF transporter
Locus tag: RoseRS_0561
Name: cbiN
Funciton: Additional substrate-specific component CbiN of cobalt ECF transporter
Locus tag: RoseRS_0562
Name: cbiQ
Funciton: Transmembrane component CbiQ of energizing module of cobalt ECF transporter
Locus tag: RoseRS_0563
Name: cbiO
Funciton: ATPase component CbiO of energizing module of cobalt ECF transporter
Locus tag: RoseRS_0564
Name: cbiB
Funciton: Adenosylcobinamide-phosphate synthase
Locus tag: RoseRS_0565
Name: cbiX
Funciton: Sirohydrochlorin cobaltochelatase (EC 4.99.1.3)
Locus tag: RoseRS_0566
Name: wrbA
Funciton: multimeric flavodoxin WrbA-like protein
Locus tag: RoseRS_0567
Name: cbiC
Funciton: Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)
Locus tag: RoseRS_0568
Name: cbiD
Funciton: Cobalt-precorrin-6 synthase, anaerobic
Locus tag: RoseRS_0569
Name: cbiET
Funciton: Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-) / Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-)
Locus tag: RoseRS_0570
Name: cbiL
Funciton: Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)
Locus tag: RoseRS_0571
Name: cbiF
Funciton: Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)
Locus tag: RoseRS_0572
Name: cbiGH
Funciton: Cobalamin biosynthesis protein CbiG / Cobalt-precorrin-3b C17-methyltransferase
Locus tag: RoseRS_0573
Name: cobA
Funciton: Uroporphyrinogen-III methyltransferase (EC 2.1.1.107)
Locus tag: RoseRS_0574
Name: cbiA
Funciton: Cobyrinic acid A,C-diamide synthase
Locus tag: RoseRS_0575
Name: cobU
Funciton: Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62)
Locus tag: RoseRS_0576
Name: cobD
Funciton: L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81)
Locus tag: RoseRS_0577
Name: cbiP
Funciton: Cobyric acid synthase
btuR
Cob(I)alamin adenosyltransferase (EC 2.5.1.17)
cobN
CobN component of cobalt chelatase involved in B12 biosynthesis
cobT
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21)
cbiM
Substrate-specific component CbiM of cobalt ECF transporter
cbiN
Additional substrate-specific component CbiN of cobalt ECF transporter
cbiQ
Transmembrane component CbiQ of energizing module of cobalt ECF transporter
cbiO
ATPase component CbiO of energizing module of cobalt ECF transporter
cbiB
Adenosylcobinamide-phosphate synthase
cbiX
Sirohydrochlorin cobaltochelatase (EC 4.99.1.3)
wrbA
multimeric flavodoxin WrbA-like protein
cbiC
Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)
cbiD
Cobalt-precorrin-6 synthase, anaerobic
cbiET
Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-) / Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-)
cbiL
Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)
cbiF
Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)
cbiGH
Cobalamin biosynthesis protein CbiG / Cobalt-precorrin-3b C17-methyltransferase
cobA
Uroporphyrinogen-III methyltransferase (EC 2.1.1.107)
cbiA
Cobyrinic acid A,C-diamide synthase
cobU
Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62)
cobD
L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81)
cbiP
Cobyric acid synthase

Position: -197
Score: 65.4
Sequence: CAAGTGAATACCATC...
Locus tag: RoseRS_3085
Name: null
Funciton: hypothetical protein
Locus tag: RoseRS_3086
Name: btuF
Funciton: Vitamin B12 ABC transporter, B12-binding component BtuF
Locus tag: RoseRS_3087
Name: cbiW
Funciton: ferredoxin-like protein
Locus tag: RoseRS_3088
Name: btuC
Funciton: Vitamin B12 ABC transporter, permease component BtuC
Locus tag: RoseRS_3089
Name: btuD
Funciton: Vitamin B12 ABC transporter, ATP-binding component BtuD
hypothetical protein
btuF
Vitamin B12 ABC transporter, B12-binding component BtuF
cbiW
ferredoxin-like protein
btuC
Vitamin B12 ABC transporter, permease component BtuC
btuD
Vitamin B12 ABC transporter, ATP-binding component BtuD
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