Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 4.0 --

Regulon of Cobalamin in Chloroflexus aggregans DSM 9485

Properties
Regulator type: RNA regulatory element
Name: Cobalamin
RFAM: RF00174
Regulation mode:
Biological process: Cobalamin biosynthesis
Effector: Adenosylcobalamin
Regulog: Cobalamin - Chloroflexia
Under regulation:
- Genes 26
- Operons 2
Member of regulog collections
Regulated operons
Locus Tag Name Function

Position: -262
Score: 62.7
Sequence: GCAATTCCATACTCA...
Locus tag: Cagg_1279
Name: btuR
Funciton: Cob(I)alamin adenosyltransferase (EC 2.5.1.17)
Locus tag: Cagg_1278
Name: cobN
Funciton: CobN component of cobalt chelatase involved in B12 biosynthesis
Locus tag: Cagg_1277
Name: cobT
Funciton: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21)
Locus tag: Cagg_1276
Name: cbiM
Funciton: Substrate-specific component CbiM of cobalt ECF transporter
Locus tag: Cagg_1275
Name: cbiN
Funciton: Additional substrate-specific component CbiN of cobalt ECF transporter
Locus tag: Cagg_1274
Name: cbiQ
Funciton: Transmembrane component CbiQ of energizing module of cobalt ECF transporter
Locus tag: Cagg_1273
Name: cbiO
Funciton: ATPase component CbiO of energizing module of cobalt ECF transporter
Locus tag: Cagg_1272
Name: cbiB
Funciton: Adenosylcobinamide-phosphate synthase
Locus tag: Cagg_1271
Name: cbiX
Funciton: Sirohydrochlorin cobaltochelatase (EC 4.99.1.3)
Locus tag: Cagg_1270
Name: wrbA
Funciton: multimeric flavodoxin WrbA-like protein
Locus tag: Cagg_1269
Name: cbiC
Funciton: Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)
Locus tag: Cagg_1268
Name: cbiD
Funciton: Cobalt-precorrin-6 synthase, anaerobic
Locus tag: Cagg_1267
Name: cbiET
Funciton: Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-) / Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-)
Locus tag: Cagg_1266
Name: cbiL
Funciton: Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)
Locus tag: Cagg_1265
Name: cbiF
Funciton: Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)
Locus tag: Cagg_1264
Name: cbiGH
Funciton: Cobalamin biosynthesis protein CbiG / Cobalt-precorrin-3b C17-methyltransferase
Locus tag: Cagg_1263
Name: cobA
Funciton: Uroporphyrinogen-III methyltransferase (EC 2.1.1.107)
Locus tag: Cagg_1262
Name: cbiA
Funciton: Cobyrinic acid A,C-diamide synthase
Locus tag: Cagg_1261
Name: cobU
Funciton: Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62)
Locus tag: Cagg_1260
Name: cobD
Funciton: L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81)
Locus tag: Cagg_1259
Name: cbiP
Funciton: Cobyric acid synthase
btuR
Cob(I)alamin adenosyltransferase (EC 2.5.1.17)
cobN
CobN component of cobalt chelatase involved in B12 biosynthesis
cobT
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21)
cbiM
Substrate-specific component CbiM of cobalt ECF transporter
cbiN
Additional substrate-specific component CbiN of cobalt ECF transporter
cbiQ
Transmembrane component CbiQ of energizing module of cobalt ECF transporter
cbiO
ATPase component CbiO of energizing module of cobalt ECF transporter
cbiB
Adenosylcobinamide-phosphate synthase
cbiX
Sirohydrochlorin cobaltochelatase (EC 4.99.1.3)
wrbA
multimeric flavodoxin WrbA-like protein
cbiC
Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)
cbiD
Cobalt-precorrin-6 synthase, anaerobic
cbiET
Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-) / Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-)
cbiL
Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)
cbiF
Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)
cbiGH
Cobalamin biosynthesis protein CbiG / Cobalt-precorrin-3b C17-methyltransferase
cobA
Uroporphyrinogen-III methyltransferase (EC 2.1.1.107)
cbiA
Cobyrinic acid A,C-diamide synthase
cobU
Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62)
cobD
L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81)
cbiP
Cobyric acid synthase

Position: -313
Score: 47.3
Sequence: TGTATCACCCCACCG...
Locus tag: Cagg_2179
Name: cbrX
Funciton: LPXTG-motif cell wall anchor domain protein
Locus tag: Cagg_2178
Name: cbrY
Funciton: hypothetical secreted protein, a putative component of B12 transporter, anchored in the membrane
Locus tag: Cagg_2177
Name: cobC
Funciton: Alpha-ribazole-5'-phosphate phosphatase (EC 3.1.3.73)
Locus tag: Cagg_2176
Name: cobS
Funciton: Cobalamin 5'-phosphate synthase
Locus tag: Cagg_2175
Name: cbrV
Funciton: Transmembrane component CbrV of energizing module of predicted cobalamin ECF transporter
cbrX
LPXTG-motif cell wall anchor domain protein
cbrY
hypothetical secreted protein, a putative component of B12 transporter, anchored in the membrane
cobC
Alpha-ribazole-5'-phosphate phosphatase (EC 3.1.3.73)
cobS
Cobalamin 5'-phosphate synthase
cbrV
Transmembrane component CbrV of energizing module of predicted cobalamin ECF transporter
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