Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 4.0 --

Regulog MleR - Lactobacillaceae

Properties
Regulator type: Transcription factor
Regulator family: LysR
Regulation mode: activator
Biological process: Malate utilization
Effector: L-malate
Phylum: Firmicutes
Visualization:
Allows to visualize regulog content in the context of metabolic pathways
Built upon 21 sites [see more]
Member of regulog collections
Statistics of regulated genes
Genome Genes Operons
Lactobacillus acidophilus NCFM 1 1
Lactobacillus brevis ATCC 367 3 2
Lactobacillus casei ATCC 334 3 2
Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365
Lactobacillus fermentum IFO 3956
Lactobacillus helveticus DPC 4571
Lactobacillus johnsonii NCC 533
Lactobacillus plantarum WCFS1 3 2
Lactobacillus reuteri JCM 1112 2 2
Lactobacillus rhamnosus GG 3 2
Lactobacillus sakei subsp. sakei 23K 3 2
Lactobacillus salivarius subsp. salivarius UCC118 3 2
Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 3 2
Oenococcus oeni PSU-1 3 2
Pediococcus pentosaceus ATCC 25745 3 2
Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes Function
 
CRON 1.
mleS
*
Lactobacillus acidophilus NCFM

Site:
position = -363
score = 4.65449
sequence = TATTAATTTCATTTAAA

Gene: LBA1075: Malolactic enzyme
*
Lactobacillus brevis ATCC 367

Site:
position = -103
score = 6.02285
sequence = TATAAAATAATTTTATA

Gene: LVIS_2203: Malolactic enzyme
*
Lactobacillus casei ATCC 334

Site:
position = -389
score = 5.68157
sequence = TATAAAAATATTTTATC

Gene: LSEI_0740: Malolactic enzyme
 
Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365
 
Lactobacillus fermentum IFO 3956
 
Lactobacillus helveticus DPC 4571
 
Lactobacillus johnsonii NCC 533
*
Lactobacillus plantarum WCFS1

Site:
position = -138
score = 5.35247
sequence = TATTTAATATATTTATA

Gene: lp_1118: Malolactic enzyme
*
Lactobacillus reuteri JCM 1112

Site:
position = -100
score = 5.65007
sequence = TATCAATTTTATTTATA

Gene: LAR_1441: Malolactic enzyme
*
Lactobacillus rhamnosus GG

Site:
position = -118
score = 5.68157
sequence = TATAAAAATATTTTATC

Gene: LGG_00726: Malolactic enzyme
*
Lactobacillus sakei subsp. sakei 23K

Site:
position = -97
score = 5.33265
sequence = TATAAATCTATTTTATC

Gene: LSA0441: Malolactic enzyme
*
Lactobacillus salivarius subsp. salivarius UCC118

Site:
position = -107
score = 5.72838
sequence = TATAAATAATATTAATA

Gene: LSL_1313: Malolactic enzyme
*
Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293

Site:
position = -106
score = 6.02285
sequence = TATAAAATAAATTTATA

Gene: LEUM_1005: Malolactic enzyme
*
Oenococcus oeni PSU-1

Site:
position = -83
score = 5.08913
sequence = TATAAGATAATTTTATC

Gene: OEOE_1564: Malolactic enzyme
*
Pediococcus pentosaceus ATCC 25745

Site:
position = -91
score = 6.00112
sequence = TATAAAAAATATTTATA

Gene: PEPE_1617: Malolactic enzyme
Malolactic enzyme
mleP
 
Lactobacillus acidophilus NCFM
 
Lactobacillus brevis ATCC 367

Gene: LVIS_2202: L-malate permease
 
Lactobacillus casei ATCC 334

Gene: LSEI_0741: L-malate permease
 
Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365
 
Lactobacillus fermentum IFO 3956
 
Lactobacillus helveticus DPC 4571
 
Lactobacillus johnsonii NCC 533
 
Lactobacillus plantarum WCFS1

Gene: lp_1119: L-malate permease
 
Lactobacillus reuteri JCM 1112
 
Lactobacillus rhamnosus GG

Gene: LGG_00727: L-malate permease
 
Lactobacillus sakei subsp. sakei 23K

Gene: LSA0442: L-malate permease
 
Lactobacillus salivarius subsp. salivarius UCC118

Gene: LSL_1312: L-malate permease
 
Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293

Gene: LEUM_1006: L-malate permease
 
Oenococcus oeni PSU-1

Gene: OEOE_1563: L-malate permease
 
Pediococcus pentosaceus ATCC 25745

Gene: PEPE_1616: L-malate permease
L-malate permease
 
CRON 2.
mleR
 
Lactobacillus acidophilus NCFM

Gene: LBA1074: Malate utilization transcrtional regulator MleR, LysR family
*
Lactobacillus brevis ATCC 367

Site:
position = -52
score = 6.02285
sequence = TATAAAATTATTTTATA

Gene: LVIS_2204: Malate utilization transcrtional regulator MleR, LysR family
*
Lactobacillus casei ATCC 334

Site:
position = -76
score = 5.68157
sequence = GATAAAATATTTTTATA

Gene: LSEI_0739: Malate utilization transcrtional regulator MleR, LysR family
 
Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365
 
Lactobacillus fermentum IFO 3956

Gene: LAF_1565: Malate utilization transcrtional regulator MleR, LysR family
 
Lactobacillus helveticus DPC 4571
 
Lactobacillus johnsonii NCC 533
*2
Lactobacillus plantarum WCFS1

Gene: lp_1115: Malate utilization transcrtional regulator MleR, LysR family

Site:
position = -53
score = 5.35247
sequence = TATAAATATATTAAATA

Gene: lp_1116: Malate utilization transcrtional regulator MleR, LysR family
*2
Lactobacillus reuteri JCM 1112

Site:
position = -53
score = 5.65007
sequence = TATAAATAAAATTGATA

Gene: LAR_1442: Malate utilization transcrtional regulator MleR, LysR family

Gene: LAR_1437: Malate utilization transcrtional regulator MleR, LysR family
*
Lactobacillus rhamnosus GG

Site:
position = -322
score = 5.68157
sequence = GATAAAATATTTTTATA

Gene: LGG_00725: Malate utilization transcrtional regulator MleR, LysR family
*
Lactobacillus sakei subsp. sakei 23K

Site:
position = -51
score = 5.33265
sequence = GATAAAATAGATTTATA

Gene: LSA0440: Malate utilization transcrtional regulator MleR, LysR family
*
Lactobacillus salivarius subsp. salivarius UCC118

Site:
position = -51
score = 5.72838
sequence = TATTAATATTATTTATA

Gene: LSL_1314: Malate utilization transcrtional regulator MleR, LysR family
*
Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293

Site:
position = -53
score = 6.02285
sequence = TATAAATTTATTTTATA

Gene: LEUM_1004: Malate utilization transcrtional regulator MleR, LysR family
*
Oenococcus oeni PSU-1

Site:
position = -16
score = 5.08913
sequence = GATAAAATTATCTTATA

Gene: OEOE_1565: Malate utilization transcrtional regulator MleR, LysR family
*
Pediococcus pentosaceus ATCC 25745

Site:
position = -61
score = 6.00112
sequence = TATAAATATTTTTTATA

Gene: PEPE_1618: Malate utilization transcrtional regulator MleR, LysR family
Malate utilization transcrtional regulator MleR, LysR family
Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.
Red color - the gene is in non-regulated operon.
Gray color - the orthologous gene is absent.
The star symbol - the TFBS is located in upstream region of this gene.
The number - the numeber of homologs (shown only if it is greater than one).
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