Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 4.0 --

Regulog T-box(Cys) - Clostridiaceae

Properties
Regulator type: RNA regulatory element
Name: T-box
RFAM: RF00230
Regulation mode:
Biological process: Amino acid metabolism
Effector: Cys-tRNA
Phylum: Firmicutes
Member of regulog collections
Statistics of regulated genes
Genome Genes Operons
Clostridium kluyveri DSM 555 5 2
Clostridium sp. SS2/1 2 1
Clostridium cellulolyticum H10
Clostridium phytofermentans ISDg 2 1
Clostridium tetani E88 1 1
Clostridium acetobutylicum ATCC 824 7 3
Clostridium botulinum A str. ATCC 3502 7 3
Clostridium novyi NT 1 1
Clostridium perfringens ATCC 13124 8 4
Clostridium difficile 630
Clostridium beijerincki NCIMB 8052 2 1
Clostridium sp. OhILAs 2 1
Clostridium sp. L2-50
Clostridium scindens ATCC 35704 2 1
Clostridium nexile DSM 1787 2 1
Clostridium leptum DSM 753
Clostridium hiranonis DSM 13275
Clostridium butyricum 5521 2 1
Clostridium bolteae ATCC BAA-613
Clostridium bartlettii DSM 16795
Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes Function
 
CRON 1.
cysK
*
Clostridium kluyveri DSM 555

Site:
position = -330
score = 115.07
sequence = CAGAAATACTTTGAA...

Gene: CKL_3413: Cysteine synthase (EC 2.5.1.47)
 
Clostridium sp. SS2/1
 
Clostridium cellulolyticum H10
 
Clostridium phytofermentans ISDg
 
Clostridium tetani E88
 
Clostridium acetobutylicum ATCC 824
*
Clostridium botulinum A str. ATCC 3502

Site:
position = -297
score = 121.73
sequence = TAAAAACGTTGAAAA...

Gene: CBO0205: Cysteine synthase (EC 2.5.1.47)
 
Clostridium novyi NT
*
Clostridium perfringens ATCC 13124

Site:
position = -281
score = 109.74
sequence = GATAAATGTTGTGAT...

Gene: CPF_1529: Cysteine synthase (EC 2.5.1.47)
 
Clostridium difficile 630

Gene: CD1594: Cysteine synthase (EC 2.5.1.47)
*
Clostridium beijerincki NCIMB 8052

Site:
position = -267
score = 47.79
sequence = TTAAAAAATGGAGCG...

Gene: Cbei_0577: Cysteine synthase (EC 2.5.1.47)
 
Clostridium sp. OhILAs
 
Clostridium sp. L2-50
 
Clostridium scindens ATCC 35704
 
Clostridium nexile DSM 1787
 
Clostridium leptum DSM 753
 
Clostridium hiranonis DSM 13275

Gene: CLOHIR_01723: Cysteine synthase (EC 2.5.1.47)
*
Clostridium butyricum 5521

Site:
position = -477
score = 117.88
sequence = TAAAAACTATGAAAA...

Gene: CBY_4054: Cysteine synthase (EC 2.5.1.47)
 
Clostridium bolteae ATCC BAA-613
 
Clostridium bartlettii DSM 16795

Gene: CLOBAR_02045: Cysteine synthase (EC 2.5.1.47)
Cysteine synthase (EC 2.5.1.47)
cysE
 
Clostridium kluyveri DSM 555

Gene: CKL_3412: Serine acetyltransferase (EC 2.3.1.30)
*
Clostridium sp. SS2/1

Site:
position = -225
score = 101.99
sequence = TAAATGCAATGAACA...

Gene: CLOSS21_00208: Serine acetyltransferase (EC 2.3.1.30)
 
Clostridium cellulolyticum H10

Gene: Ccel_3325: Serine acetyltransferase (EC 2.3.1.30)
*
Clostridium phytofermentans ISDg

Site:
position = -370
score = 114.37
sequence = GTGAAAAGCATTGAT...

Gene: null: Serine acetyltransferase (EC 2.3.1.30)
*
Clostridium tetani E88

Site:
position = -282
score = 92.12
sequence = AAAATACATTGAAAG...

Gene: CTC00351: Serine acetyltransferase (EC 2.3.1.30)
*
Clostridium acetobutylicum ATCC 824

Site:
position = -269
score = 88.99
sequence = GAAATGCTTTGATAA...

Gene: CAC0687: Serine acetyltransferase (EC 2.3.1.30)
 
Clostridium botulinum A str. ATCC 3502

Gene: CBO0206: Serine acetyltransferase (EC 2.3.1.30)
*
Clostridium novyi NT

Site:
position = -305
score = 75.35
sequence = GAAATACAGTGAAGA...

Gene: NT01CX_1391: Serine acetyltransferase (EC 2.3.1.30)
 
Clostridium perfringens ATCC 13124

Gene: CPF_1528: Serine acetyltransferase (EC 2.3.1.30)
 
Clostridium difficile 630

Gene: CD1595: Serine acetyltransferase (EC 2.3.1.30)
 2
Clostridium beijerincki NCIMB 8052

Gene: Cbei_0247: Serine acetyltransferase (EC 2.3.1.30)

Gene: Cbei_0578: Serine acetyltransferase (EC 2.3.1.30)
*
Clostridium sp. OhILAs

Site:
position = -315
score = 107.52
sequence = AAAAAGCGAAGAACA...

Gene: Clos_0468: Serine acetyltransferase (EC 2.3.1.30)
 
Clostridium sp. L2-50
*
Clostridium scindens ATCC 35704

Site:
position = -305
score = 101.99
sequence = AAAAGACGCTGAACG...

Gene: CLOSCI_01225: Serine acetyltransferase (EC 2.3.1.30)
*
Clostridium nexile DSM 1787

Site:
position = -311
score = 110.11
sequence = GAGAAAGACTTAGAA...

Gene: CLONEX_00247: Serine acetyltransferase (EC 2.3.1.30)
 
Clostridium leptum DSM 753

Gene: CLOLEP_01986: Serine acetyltransferase (EC 2.3.1.30)
 
Clostridium hiranonis DSM 13275

Gene: CLOHIR_01722: Serine acetyltransferase (EC 2.3.1.30)
 
Clostridium butyricum 5521

Gene: CBY_4055: Serine acetyltransferase (EC 2.3.1.30)
 
Clostridium bolteae ATCC BAA-613

Gene: CLOBOL_04948: Serine acetyltransferase (EC 2.3.1.30)
 
Clostridium bartlettii DSM 16795

Gene: CLOBAR_02044: Serine acetyltransferase (EC 2.3.1.30)
Serine acetyltransferase (EC 2.3.1.30)
cysS
 
Clostridium kluyveri DSM 555

Gene: CKL_0201: Cysteinyl-tRNA synthetase (EC 6.1.1.16)
 
Clostridium sp. SS2/1

Gene: CLOSS21_00209: Cysteinyl-tRNA synthetase (EC 6.1.1.16)
 
Clostridium cellulolyticum H10

Gene: Ccel_3324: Cysteinyl-tRNA synthetase (EC 6.1.1.16)
 
Clostridium phytofermentans ISDg

Gene: null: Cysteinyl-tRNA synthetase (EC 6.1.1.16)
 
Clostridium tetani E88

Gene: CTC02622: Cysteinyl-tRNA synthetase (EC 6.1.1.16)
 
Clostridium acetobutylicum ATCC 824

Gene: CAC3177: Cysteinyl-tRNA synthetase (EC 6.1.1.16)
 
Clostridium botulinum A str. ATCC 3502

Gene: CBO3501: Cysteinyl-tRNA synthetase (EC 6.1.1.16)
 
Clostridium novyi NT

Gene: NT01CX_1093: Cysteinyl-tRNA synthetase (EC 6.1.1.16)
 
Clostridium perfringens ATCC 13124

Gene: CPF_2737: Cysteinyl-tRNA synthetase (EC 6.1.1.16)
 
Clostridium difficile 630

Gene: CD0052: Cysteinyl-tRNA synthetase (EC 6.1.1.16)
 
Clostridium beijerincki NCIMB 8052

Gene: Cbei_0131: Cysteinyl-tRNA synthetase (EC 6.1.1.16)
 
Clostridium sp. OhILAs

Gene: Clos_0469: Cysteinyl-tRNA synthetase (EC 6.1.1.16)
 
Clostridium sp. L2-50

Gene: CLOL250_00902: Cysteinyl-tRNA synthetase (EC 6.1.1.16)
 
Clostridium scindens ATCC 35704

Gene: CLOSCI_01226: Cysteinyl-tRNA synthetase (EC 6.1.1.16)
 
Clostridium nexile DSM 1787

Gene: CLONEX_00246: Cysteinyl-tRNA synthetase (EC 6.1.1.16)
 
Clostridium leptum DSM 753

Gene: CLOLEP_01987: Cysteinyl-tRNA synthetase (EC 6.1.1.16)
 
Clostridium hiranonis DSM 13275

Gene: CLOHIR_01557: Cysteinyl-tRNA synthetase (EC 6.1.1.16)
 
Clostridium butyricum 5521

Gene: CBY_2150: Cysteinyl-tRNA synthetase (EC 6.1.1.16)
 
Clostridium bolteae ATCC BAA-613

Gene: CLOBOL_02763: Cysteinyl-tRNA synthetase (EC 6.1.1.16)
 
Clostridium bartlettii DSM 16795

Gene: CLOBAR_00070: Cysteinyl-tRNA synthetase (EC 6.1.1.16)
Cysteinyl-tRNA synthetase (EC 6.1.1.16)
 
CRON 2.
cysP1
 
Clostridium kluyveri DSM 555
 
Clostridium sp. SS2/1
 
Clostridium cellulolyticum H10
 
Clostridium phytofermentans ISDg
 
Clostridium tetani E88

Gene: CTC02307: Cystine uptake protein CysP
 
Clostridium acetobutylicum ATCC 824
*
Clostridium botulinum A str. ATCC 3502

Site:
position = -395
score = 87.29
sequence = ATTAAAAGCTATGAA...

Gene: CBO0235: Cystine uptake protein CysP
 
Clostridium novyi NT

Gene: NT01CX_2260: Cystine uptake protein CysP
*
Clostridium perfringens ATCC 13124

Site:
position = -331
score = 67.64
sequence = GAAAAGCTGTGATTA...

Gene: CPF_1223: Cystine uptake protein CysP
 
Clostridium difficile 630
 
Clostridium beijerincki NCIMB 8052
 
Clostridium sp. OhILAs
 
Clostridium sp. L2-50
 
Clostridium scindens ATCC 35704

Gene: CLOSCI_02148: Cystine uptake protein CysP
 
Clostridium nexile DSM 1787

Gene: CLONEX_00437: Cystine uptake protein CysP
 
Clostridium leptum DSM 753
 
Clostridium hiranonis DSM 13275
 
Clostridium butyricum 5521
 
Clostridium bolteae ATCC BAA-613

Gene: CLOBOL_05337: Cystine uptake protein CysP
 
Clostridium bartlettii DSM 16795
Cystine uptake protein CysP
cysP2
 
Clostridium kluyveri DSM 555
 
Clostridium sp. SS2/1

Gene: CLOSS21_00450: Cystine uptake protein CysP
 
Clostridium cellulolyticum H10
 
Clostridium phytofermentans ISDg

Gene: null: Cystine uptake protein CysP
 
Clostridium tetani E88
 
Clostridium acetobutylicum ATCC 824
 
Clostridium botulinum A str. ATCC 3502
 
Clostridium novyi NT
*
Clostridium perfringens ATCC 13124

Site:
position = -376
score = 104.21
sequence = TAAATGCGTTGAAGA...

Gene: CPF_1191: Cystine uptake protein CysP
 
Clostridium difficile 630

Gene: CD2541: Cystine uptake protein CysP
 
Clostridium beijerincki NCIMB 8052

Gene: Cbei_4344: Cystine uptake protein CysP
 
Clostridium sp. OhILAs

Gene: Clos_0824: Cystine uptake protein CysP
 
Clostridium sp. L2-50
 
Clostridium scindens ATCC 35704
 
Clostridium nexile DSM 1787
 
Clostridium leptum DSM 753
 
Clostridium hiranonis DSM 13275

Gene: CLOHIR_01037: Cystine uptake protein CysP
 
Clostridium butyricum 5521
 
Clostridium bolteae ATCC BAA-613
 
Clostridium bartlettii DSM 16795

Gene: CLOBAR_01036: Cystine uptake protein CysP
Cystine uptake protein CysP
 
CRON 3.
tcyA
 
Clostridium kluyveri DSM 555
 
Clostridium sp. SS2/1
 
Clostridium cellulolyticum H10
 
Clostridium phytofermentans ISDg
 
Clostridium tetani E88
*
Clostridium acetobutylicum ATCC 824

Site:
position = -327
score = 87.38
sequence = GATTTGCTAGGATAA...

Gene: CAC3325: L-Cystine ABC transporter, periplasmic cystine-binding protein TcyA
 
Clostridium botulinum A str. ATCC 3502
 
Clostridium novyi NT
 
Clostridium perfringens ATCC 13124
 
Clostridium difficile 630
 
Clostridium beijerincki NCIMB 8052
 
Clostridium sp. OhILAs
 
Clostridium sp. L2-50
 
Clostridium scindens ATCC 35704
 
Clostridium nexile DSM 1787
 
Clostridium leptum DSM 753
 
Clostridium hiranonis DSM 13275
 
Clostridium butyricum 5521
 
Clostridium bolteae ATCC BAA-613

Gene: CLOBOL_06445: L-Cystine ABC transporter, periplasmic cystine-binding protein TcyA
 
Clostridium bartlettii DSM 16795
L-Cystine ABC transporter, periplasmic cystine-binding protein TcyA
tcyB
 
Clostridium kluyveri DSM 555
 
Clostridium sp. SS2/1
 
Clostridium cellulolyticum H10
 
Clostridium phytofermentans ISDg
 
Clostridium tetani E88
 
Clostridium acetobutylicum ATCC 824

Gene: CAC3326: L-Cystine ABC transporter, permease protein TcyB
 
Clostridium botulinum A str. ATCC 3502
 
Clostridium novyi NT
 
Clostridium perfringens ATCC 13124
 
Clostridium difficile 630
 
Clostridium beijerincki NCIMB 8052
 
Clostridium sp. OhILAs
 
Clostridium sp. L2-50
 
Clostridium scindens ATCC 35704
 
Clostridium nexile DSM 1787
 
Clostridium leptum DSM 753
 
Clostridium hiranonis DSM 13275
 
Clostridium butyricum 5521
 
Clostridium bolteae ATCC BAA-613

Gene: CLOBOL_06446: L-Cystine ABC transporter, permease protein TcyB
 
Clostridium bartlettii DSM 16795
L-Cystine ABC transporter, permease protein TcyB
tcyC
 
Clostridium kluyveri DSM 555
 
Clostridium sp. SS2/1
 
Clostridium cellulolyticum H10
 
Clostridium phytofermentans ISDg
 
Clostridium tetani E88
 
Clostridium acetobutylicum ATCC 824

Gene: CAC3327: L-Cystine ABC transporter, ATP-binding protein TcyC
 
Clostridium botulinum A str. ATCC 3502
 
Clostridium novyi NT
 
Clostridium perfringens ATCC 13124
 
Clostridium difficile 630
 
Clostridium beijerincki NCIMB 8052
 
Clostridium sp. OhILAs
 
Clostridium sp. L2-50
 
Clostridium scindens ATCC 35704
 
Clostridium nexile DSM 1787
 
Clostridium leptum DSM 753
 
Clostridium hiranonis DSM 13275
 
Clostridium butyricum 5521
 
Clostridium bolteae ATCC BAA-613

Gene: CLOBOL_06447: L-Cystine ABC transporter, ATP-binding protein TcyC
 
Clostridium bartlettii DSM 16795
L-Cystine ABC transporter, ATP-binding protein TcyC
 
CRON 4.
ubiG
*
Clostridium kluyveri DSM 555

Site:
position = -370
score = 84.03
sequence = TAATTGCGATGATGA...

Gene: CKL_1001: SAM-dependent methlytransferase UbiG
 
Clostridium sp. SS2/1
 
Clostridium cellulolyticum H10
 
Clostridium phytofermentans ISDg
 
Clostridium tetani E88
*
Clostridium acetobutylicum ATCC 824

Site:
position = -377
score = 98.11
sequence = TAAATACTGTGATAA...

Gene: CAC0929: SAM-dependent methlytransferase UbiG
*
Clostridium botulinum A str. ATCC 3502

Site:
position = -407
score = 98.63
sequence = GATAAATGCTATGAT...

Gene: CBO0727: SAM-dependent methlytransferase UbiG
 
Clostridium novyi NT
*
Clostridium perfringens ATCC 13124

Site:
position = -380
score = 131.38
sequence = TAAATGCATTGAAAA...

Gene: CPF_0168: SAM-dependent methlytransferase UbiG
 
Clostridium difficile 630
 
Clostridium beijerincki NCIMB 8052
 
Clostridium sp. OhILAs

Gene: Clos_1076: SAM-dependent methlytransferase UbiG
 
Clostridium sp. L2-50
 
Clostridium scindens ATCC 35704
 
Clostridium nexile DSM 1787
 
Clostridium leptum DSM 753
 
Clostridium hiranonis DSM 13275
 
Clostridium butyricum 5521
 
Clostridium bolteae ATCC BAA-613
 
Clostridium bartlettii DSM 16795
SAM-dependent methlytransferase UbiG
mccB
 
Clostridium kluyveri DSM 555

Gene: CKL_1002: Cystathionine gamma-lyase (EC 4.4.1.1)
 
Clostridium sp. SS2/1
 
Clostridium cellulolyticum H10
 
Clostridium phytofermentans ISDg

Gene: null: Cystathionine gamma-lyase (EC 4.4.1.1)
 
Clostridium tetani E88
 
Clostridium acetobutylicum ATCC 824

Gene: CAC0930: Cystathionine gamma-lyase (EC 4.4.1.1)
 
Clostridium botulinum A str. ATCC 3502

Gene: CBO0726: Cystathionine gamma-lyase (EC 4.4.1.1)
 
Clostridium novyi NT
 
Clostridium perfringens ATCC 13124

Gene: CPF_0169: Cystathionine gamma-lyase (EC 4.4.1.1)
 
Clostridium difficile 630
 
Clostridium beijerincki NCIMB 8052

Gene: Cbei_0629: Cystathionine gamma-lyase (EC 4.4.1.1)
 
Clostridium sp. OhILAs

Gene: Clos_1074: Cystathionine gamma-lyase (EC 4.4.1.1)
 
Clostridium sp. L2-50
 
Clostridium scindens ATCC 35704
 
Clostridium nexile DSM 1787
 
Clostridium leptum DSM 753
 
Clostridium hiranonis DSM 13275
 
Clostridium butyricum 5521

Gene: CBY_1162: Cystathionine gamma-lyase (EC 4.4.1.1)
 
Clostridium bolteae ATCC BAA-613
 
Clostridium bartlettii DSM 16795
Cystathionine gamma-lyase (EC 4.4.1.1)
mccA
 
Clostridium kluyveri DSM 555

Gene: CKL_1003: Cystathionine beta-synthase (EC 4.2.1.22)
 
Clostridium sp. SS2/1
 
Clostridium cellulolyticum H10
 
Clostridium phytofermentans ISDg

Gene: null: Cystathionine beta-synthase (EC 4.2.1.22)
 
Clostridium tetani E88
 
Clostridium acetobutylicum ATCC 824

Gene: CAC0931: Cystathionine beta-synthase (EC 4.2.1.22)
 
Clostridium botulinum A str. ATCC 3502

Gene: CBO0724: Cystathionine beta-synthase (EC 4.2.1.22)
 
Clostridium novyi NT
 
Clostridium perfringens ATCC 13124

Gene: CPF_0170: Cystathionine beta-synthase (EC 4.2.1.22)
 
Clostridium difficile 630
 
Clostridium beijerincki NCIMB 8052

Gene: Cbei_0630: Cystathionine beta-synthase (EC 4.2.1.22)
 
Clostridium sp. OhILAs

Gene: Clos_1073: Cystathionine beta-synthase (EC 4.2.1.22)
 
Clostridium sp. L2-50
 
Clostridium scindens ATCC 35704
 
Clostridium nexile DSM 1787
 
Clostridium leptum DSM 753
 
Clostridium hiranonis DSM 13275
 
Clostridium butyricum 5521

Gene: CBY_1163: Cystathionine beta-synthase (EC 4.2.1.22)
 
Clostridium bolteae ATCC BAA-613
 
Clostridium bartlettii DSM 16795
Cystathionine beta-synthase (EC 4.2.1.22)
luxS
 
Clostridium kluyveri DSM 555

Gene: CKL_1558: S-ribosylhomocysteine lyase (EC 4.4.1.21)
 
Clostridium sp. SS2/1
 
Clostridium cellulolyticum H10
 
Clostridium phytofermentans ISDg

Gene: null: S-ribosylhomocysteine lyase (EC 4.4.1.21)
 
Clostridium tetani E88
 
Clostridium acetobutylicum ATCC 824

Gene: CAC2942: S-ribosylhomocysteine lyase (EC 4.4.1.21)
 
Clostridium botulinum A str. ATCC 3502

Gene: CBO0725: S-ribosylhomocysteine lyase (EC 4.4.1.21)
 
Clostridium novyi NT
 
Clostridium perfringens ATCC 13124

Gene: CPF_0171: S-ribosylhomocysteine lyase (EC 4.4.1.21)
 
Clostridium difficile 630

Gene: CD3598: S-ribosylhomocysteine lyase (EC 4.4.1.21)
 
Clostridium beijerincki NCIMB 8052

Gene: Cbei_1237: S-ribosylhomocysteine lyase (EC 4.4.1.21)
 
Clostridium sp. OhILAs

Gene: Clos_1075: S-ribosylhomocysteine lyase (EC 4.4.1.21)
 
Clostridium sp. L2-50

Gene: CLOL250_01391: S-ribosylhomocysteine lyase (EC 4.4.1.21)
 
Clostridium scindens ATCC 35704

Gene: CLOSCI_01289: S-ribosylhomocysteine lyase (EC 4.4.1.21)
 
Clostridium nexile DSM 1787

Gene: CLONEX_03062: S-ribosylhomocysteine lyase (EC 4.4.1.21)
 
Clostridium leptum DSM 753

Gene: CLOLEP_00535: S-ribosylhomocysteine lyase (EC 4.4.1.21)
 
Clostridium hiranonis DSM 13275

Gene: CLOHIR_02203: S-ribosylhomocysteine lyase (EC 4.4.1.21)
 
Clostridium butyricum 5521

Gene: CBY_0312: S-ribosylhomocysteine lyase (EC 4.4.1.21)
 
Clostridium bolteae ATCC BAA-613

Gene: CLOBOL_01686: S-ribosylhomocysteine lyase (EC 4.4.1.21)
 
Clostridium bartlettii DSM 16795

Gene: CLOBAR_00200: S-ribosylhomocysteine lyase (EC 4.4.1.21)
S-ribosylhomocysteine lyase (EC 4.4.1.21)
Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.
Red color - the gene is in non-regulated operon.
Gray color - the orthologous gene is absent.
The star symbol - the TFBS is located in upstream region of this gene.
The number - the numeber of homologs (shown only if it is greater than one).
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