Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 4.0 --

Propagation of Rex regulog to Staphylococcus aureus subsp. aureus COL

Reference regulog properties
Source regulog: Rex - Staphylococcaceae
Regulator type: Transcription factor
Regulator family: Rex
Regulation mode: repressor
Biological process: Energy metabolism
Effector: NADH
Phylum: Firmicutes
Propagated regulon:
Target genome Staphylococcus aureus subsp. aureus COL
Orthologous TF(s) SACOL2035
Regulated genes 15
Built upon 74 sites [see more]
Predicted regulatory interactions in Staphylococcus aureus subsp. aureus COL
Locus tag Position Score Sequence
Position: -85
Score: 4.9
Sequence: CTGTGATTTTTTACACAA
Locus tag: SACOL0019
SACOL0019 -85 4.9 CTGTGATTTTTTACACAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: vicR
Ortholog function: cell wall homeostasis regulation two-component system, response regulator
Staphylococcus aureus subsp. aureus N315 SA0017 -79 4.9 CTGTGATTTTTTACACAA
Position: -39
Score: 6.3
Sequence: TTGTGAAATAATTCACAA
Locus tag: SACOL0135
SACOL0135 -39 6.3 TTGTGAAATAATTCACAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: adhE
Ortholog function: Alcohol dehydrogenase (EC 1.1.1.1), Fe-dependent; Acetaldehyde dehydrogenase (EC 1.2.1.10)
Staphylococcus aureus subsp. aureus N315 SA0143 -39 6.3 TTGTGAAATAATTCACAA
Staphylococcus epidermidis ATCC 12228 SE0506 -38 6.1 TTGTGAATTATTTCACAA
Position: -96
Score: 6
Sequence: ATGTGAAAAAAATCACAA
Locus tag: SACOL0204
SACOL0204 -96 6 ATGTGAAAAAAATCACAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: pflB
Ortholog function: Pyruvate formate-lyase (EC 2.3.1.54)
Staphylococcus aureus subsp. aureus N315 SA0218 -96 6 ATGTGAAAAAAATCACAA
Staphylococcus epidermidis ATCC 12228 SE0214 -74 5.8 ATGTGAAATTAATCACAT
Staphylococcus carnosus subsp. carnosus TM300 Sca_2017 -93 5.3 AAGTGATTTTTTTCACAA
Macrococcus caseolyticus JCSC5402 MCCL_0434 -74 4.7 TTGTGATACTTTTCACGT
Position: -227
Score: 6
Sequence: ATGTGAAATAAATCACAA
Position: -169
Score: 6
Sequence: ATGTGAAATAAATCACAA
Locus tag: SACOL0222
SACOL0222 -227 6 ATGTGAAATAAATCACAA
-169 6 ATGTGAAATAAATCACAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: ldh
Ortholog function: L-lactate dehydrogenase (EC:1.1.1.27)
Staphylococcus aureus subsp. aureus N315 SA0232 -227 6 ATGTGAAATAAATCACAA
-169 6 ATGTGAAATAAATCACAA
Staphylococcus carnosus subsp. carnosus TM300 Sca_1369 -55 5.5 ATGTGAAATAAATCATAT
Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 SSP1001 -113 6.1 TTGTGAAATAAATCACAA
-55 6.1 TTGTGAAATAAATCACAA
Macrococcus caseolyticus JCSC5402 MCCL_0163 -142 6.1 TTGTGAAAATAATCACAA
Position: -51
Score: 6.2
Sequence: TTGTGAAATTATTCACAA
Locus tag: SACOL0301
SACOL0301 -51 6.2 TTGTGAAATTATTCACAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: nirC
Ortholog function: Formate/nitrite family of transporters
Staphylococcus aureus subsp. aureus N315 SA0293 -72 6.2 TTGTGAAATTATTCACAA
Staphylococcus carnosus subsp. carnosus TM300 Sca_1814 -75 5.9 TTGTGAAAGTATTCACAA
Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 SSP0590 -71 6.2 TTGTGAAAATATTCACAA
Position: -306
Score: 6
Sequence: TTGTGAATTAATTCACAT
Locus tag: SACOL0660
SACOL0660 -306 6 TTGTGAATTAATTCACAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: adh1/adhB
Ortholog function: Alcohol dehydrogenase (EC 1.1.1.1), Zn-dependent
Staphylococcus aureus subsp. aureus N315 SA0562 -306 6 TTGTGAATTAATTCACAT
Position: -38
Score: 6.2
Sequence: TTGTGAAATTATTCACAA
Locus tag: SACOL1478
SACOL1478 -38 6.2 TTGTGAAATTATTCACAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: ald1
Ortholog function: Alanine dehydrogenase (EC 1.4.1.1)
Staphylococcus aureus subsp. aureus N315 SA1272 -38 6.2 TTGTGAAATTATTCACAA
Position: -103
Score: 5.6
Sequence: TTGAGAATTTTTTCACAA
Locus tag: SACOL1535
SACOL1535 -103 5.6 TTGAGAATTTTTTCACAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: srrA
Ortholog function: Staphylococcal respiratory response protein SrrA
Staphylococcus aureus subsp. aureus N315 SA1323 -103 5.6 TTGAGAATTTTTTCACAA
Staphylococcus capitis SK14 STACA0001_1733 -106 5.2 TTGAGATTTTTTTCACAT
Staphylococcus epidermidis ATCC 12228 SE1176 -104 4.9 TTGATATTTTTTTCACAA
Staphylococcus haemolyticus JCSC1435 SH1424 -101 4.8 TTGCTATTTTTTTCACAA
Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 SSP1260 -105 5.1 ATGATAATTTTTTCACAA
Position: -124
Score: 6
Sequence: TTGTGAAAAAAATCACAT
Locus tag: SACOL2363
SACOL2363 -124 6 TTGTGAAAAAAATCACAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: lctP
Ortholog function: L-lactate permease
Staphylococcus aureus subsp. aureus N315 SA2156 -124 6 TTGTGAAAAAAATCACAT
Staphylococcus capitis SK14 STACA0001_1119 -129 5.9 TTGTGAAAAAGTTCACAA
Staphylococcus haemolyticus JCSC1435 SH0691 -161 5.9 TTGTGAAAAAGTTCACAA
Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 SSP0537 -76 6.3 TTGTGAAAAAATTCACAA
Position: -168
Score: 4.6
Sequence: ATGTTCACTTTTTCACAA
Locus tag: SACOL2386
SACOL2386 -168 4.6 ATGTTCACTTTTTCACAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: narK
Ortholog function: nitrate-nitrite antiporter
Staphylococcus aureus subsp. aureus N315 SA2176 -168 4.6 ATGTTCACTTTTTCACAA
Staphylococcus capitis SK14 STACA0001_1087 -156 4.9 ATGTTCATTTTTTCACAA
Staphylococcus epidermidis ATCC 12228 SE1968 -149 4.9 ATGTTCATATTTTCACAA
Staphylococcus haemolyticus JCSC1435 SH0661 -125 4.9 ATGTTCATTTTTTCACAA
Macrococcus caseolyticus JCSC5402 MCCL_0144 -73 5.1 ATGTTAAACTTATCACAA
Position: -64
Score: 5.3
Sequence: ATGTGATTCTTTTCACAA
Locus tag: SACOL2399
SACOL2399 -64 5.3 ATGTGATTCTTTTCACAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: nirR
Ortholog function: Sirohydrochlorin ferrochelatase (EC 4.99.1.4)
Staphylococcus aureus subsp. aureus N315 SA2189 -64 5.3 ATGTGATTCTTTTCACAA
Staphylococcus capitis SK14 STACA0001_1076 -64 6 ATGTGAATAAAATCACAA
Staphylococcus carnosus subsp. carnosus TM300 Sca_1899 -64 5.7 TTGTGAATACATTCACAT
Macrococcus caseolyticus JCSC5402 MCCL_1342 -91 5.8 ATGTGAACATATTCACAA
Position: -129
Score: 5.7
Sequence: TTGTGAAATACATCACAA
Locus tag: SACOL2491
SACOL2491 -129 5.7 TTGTGAAATACATCACAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: SA2268
Ortholog function: conserved hypothetical protein
Staphylococcus aureus subsp. aureus N315 SA2268 -129 5.7 TTGTGAAATACATCACAA
Staphylococcus capitis SK14 STACA0001_1015 -94 5.7 TTGTGAAAAGTATCACAA
Staphylococcus epidermidis ATCC 12228 SE2038 -91 5.7 TTGTGAAATGTATCACAA
Staphylococcus haemolyticus JCSC1435 SH0583 -87 5.7 TTGTGAAAAGTATCACAA
Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 SSP0417 -107 6.1 TTGTGAAATTAATCACAA
Position: -185
Score: 6
Sequence: TTGTGAAAAATATCACAA
Locus tag: SACOL2534
SACOL2534 -185 6 TTGTGAAAAATATCACAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: frp
Ortholog function: NAD(P)H-flavin oxidoreductase
Staphylococcus aureus subsp. aureus N315 SA2311 -185 6 TTGTGAAAAATATCACAA
Staphylococcus capitis SK14 STACA0001_0985 -197 5.8 TTGTGAAAGTTTTCACAA
Staphylococcus epidermidis ATCC 12228 SE2073 -208 4.9 TAGTAAAAACATTCACAA
-164 5.3 ATGTGATTTAATTCACTA
Staphylococcus haemolyticus JCSC1435 SH0546 -182 6.2 TTGTGAATTTATTCACAA
-133 5.6 TTGTTAAAAAATTCACAT
Position: -102
Score: 5.9
Sequence: TTGTGATATTTTTCACAA
Locus tag: SACOL2535
SACOL2535 -102 5.9 TTGTGATATTTTTCACAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: ddh
Ortholog function: D-lactate dehydrogenase (EC 1.1.1.28)
Staphylococcus aureus subsp. aureus N315 SA2312 -39 5.9 TTGTGATATTTTTCACAA
Staphylococcus capitis SK14 STACA0001_0984 -119 5.8 TTGTGAAAACTTTCACAA
Staphylococcus epidermidis ATCC 12228 SE2074 -100 5.5 TAGTGAATTAAATCACAT
-56 4.9 TTGTGAATGTTTTTACTA
Staphylococcus carnosus subsp. carnosus TM300 Sca_2121 -81 6 TTGTGAATATATTCACAT
Staphylococcus haemolyticus JCSC1435 SH0545 -203 5.5 ATGTGAATTTTTTAACAA
-154 6.2 TTGTGAATAAATTCACAA
Position: -79
Score: 5.8
Sequence: ATGTGAATATAATCACAT
Locus tag: SACOL2657
SACOL2657 -79 5.8 ATGTGAATATAATCACAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: arcA
Ortholog function: Arginine deiminase (EC 3.5.3.6)
Staphylococcus aureus subsp. aureus N315 SA2428 -79 5.8 ATGTGAATATAATCACAT
Staphylococcus capitis SK14 STACA0001_1845 -77 5.9 TTGTGAATATAATCACAT
Staphylococcus epidermidis ATCC 12228 SE2217 -76 4.8 ATGTGATAATCATCACGA